International Journal of Molecular Sciences

International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Heart Failure: From Pathogenesis to Innovative Treatments

edited by Volker Adams and

Ephraim Bernhard Winzer

submission deadline 20 Sep 2025 | Viewed by 59 | Submission Open

Keywords: heart failure; HFrEF; HFpEF; comorbidities; pathophysiology; treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Molecular-Scale and Nano-Scale Materials: Design, Characterization and Application

edited by Xiaogang Li

submission deadline 20 Sep 2025 | Viewed by 56 | Submission Open

Keywords: molecular scale; nano scale; material design and preparation; characterization; regulation; application

(This special issue belongs to the Section Molecular Nanoscience)

The Future of Biomaterials in Dentistry: Innovations in Drug Delivery and Regenerative Medicine

edited by

Victor Martin

submission deadline 20 Sep 2025 | Viewed by 54 | Submission Open

Keywords: dentistry; regenerative medicine; drug delivery; tissue engineering; biomaterials; tooth; periodontal

(This special issue belongs to the Section Materials Science)

Fundamental and Translational Insights into Colorectal Cancer

edited by Giuseppe Broggi

submission deadline 20 Sep 2025 | Viewed by 48 | Submission Open

Keywords: colorectal cancer (CRC); molecular pathways; translational research; immune checkpoint inhibitors; drug resistance

(This special issue belongs to the Section Molecular Oncology)

Mechanosensitive Ion Channels in the Nervous System

edited by

Rashid Giniatullin

submission deadline 20 Sep 2025 | Viewed by 48 | Submission Open

Keywords: mechanosensitive ion channels; Piezo1; Piezo2; mechanosensitive K2P channels; mechanical pain; pulsating blood flow; tissue stiffness; mechanobiology of glymphatic system; chemical agonists of mechanosensitive channels; mechanosensitive TRP channels; neuron; glial cells

(This special issue belongs to the Section Molecular Neurobiology)

Damage to Plants and Microorganisms Caused by Heavy Metal Toxicity

edited by

Xiaomeng Chen

submission deadline 20 Sep 2025 | Viewed by 45 | Submission Open

Keywords: metal; oxidative stress; stress response; molecular function; gene regulation; metabolic regulation; signaling pathway

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Medicinal Plants in the Treatment of Neurodegenerative Diseases: Advances, Challenges, and Future Perspectives

edited by

Katarzyna E. Stȩpnik

submission deadline 20 Sep 2025 | Viewed by 43 | Submission Open

Keywords: medicinal plants; neuroprotection; neurodegeneration; plant secondary metabolites; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Targeting Tyrosine Kinase Receptors in Cancer: Mechanisms, Resistance and Therapeutic Advances

edited by

Athina-Myrto Chioni

and

Richard Grose

submission deadline 20 Sep 2025 | Viewed by 40 | Submission Open

Keywords: tyrosine kinase receptors (TKRs); tyrosine kinase inhibitors (TKIs); cancer; therapeutic resistance/cancer drug resistance/chemotherapy resistance; signaling pathways; metastasis; combination therapy; targeted therapy; next-generation inhibitors; allosteric inhibitors; personalized medicine; tumor microenvironment; immune evasion; immunotherapy; crosstalk in cancer signaling; miRNAs; lncRNAs; cancer therapeutics; biomarkers

(This special issue belongs to the Section Molecular Oncology)

RNA in Biology and Medicine (2nd Edition)

edited by