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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Functional Studies and Deep Phenotyping in Monogenic Forms of Diabetes, Severe Insulin Resistance and Hypoglycemia
edited by Fabrizio Barbetti
submission deadline 20 Sep 2025 | Viewed by 182 | Submission Open
Keywords: monogenic diabetes; neonatal diabetes mellitus; MODY; severe insulin resistance; insulin receptor; lipodystrophy; hyperinsulinemic hypoglycemia; ABCC8/KCNJ11 dominant forms of HH
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Nanoparticle Systems for Cancer Phototherapy
edited by
submission deadline 20 Sep 2025 | Viewed by 177 | Submission Open
Keywords: nanoparticles; phototherapy; cancer; photodynamic therapy; photosensitiser molecules; biomolecules damage; DNA-intercalators; oxidative stress; cell/tissue specificity; drug delivery systems
(This special issue belongs to the Section Molecular Oncology)
Role of Glia in Human Health and Disease
edited by and
submission deadline 20 Sep 2025 | Viewed by 169 | Submission Open
Keywords: astrocytes; microglia; oligodendrocytes; Schwann cells; neurodegeneration
(This special issue belongs to the Section Molecular Neurobiology)
From Macrophage Biology to Cell and EV-Based Immunotherapies submission deadline 20 Sep 2025 | Viewed by 165 | Submission Open
Keywords: macrophage-based; macrophage-targeting; cancer immunotherapies; autoimmunity
(This special issue belongs to the Section Molecular Immunology)
The Function of Glial Cells in the Nervous System: 2nd Edition
edited by Krista Minéia Wartchow
submission deadline 20 Sep 2025 | Viewed by 165 | Submission Open
Keywords: glial cells; glial– neuronal interaction; glial biomarkers; neurodegenerative diseases; therapeutic approaches
(This special issue belongs to the Section Molecular Neurobiology)
Red Blood Cell Dysfunction and Hemodynamic Changes in Inflammation, Infection and Metabolic Disease
edited by Janette Bester
submission deadline 20 Sep 2025 | Viewed by 165 | Submission Open
Keywords: red blood cell; inflammation; infection; metabolic disease; hemodynamics
(This special issue belongs to the Section Molecular Biology)
New Insights into Ubiquitination and Deubiquitination in Plants
edited by
submission deadline 20 Sep 2025 | Viewed by 164 | Submission Open
Keywords: ubiquitin; E1; E2; E3; deubiquitination; proteolysis; plants
(This special issue belongs to the Section Biochemistry)
Molecular Research on the Regulation of Expression Associated with the Mechanism of Multidrug Resistance in Mycobacterium tuberculosis
edited by Maria Del Carmen Muñoz-Egea
submission deadline 20 Sep 2025 | Viewed by 151 | Submission Open
Keywords: multidrug resistance; MDR; XDR; Mycobacterium tuberculosis; molecular research; gene expression; genome sequencing
(This special issue belongs to the Section Molecular Microbiology)
Molecular Pathology, Diagnostics, and Therapeutics in Optic Neuropathies
edited by Tsz Kin Ng
submission deadline 20 Sep 2025 | Viewed by 140 | Submission Open
Keywords: optic neuropathies; glaucoma; optic nerve; retinal ganglion cells; neuroprotection; biomarkers; pathophysiology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
From Plant Genomics Investigations to Plant Biotechnology Exploitation
edited by
submission deadline 20 Sep 2025 | Viewed by 129 | Submission Open
Keywords: sequencing; plant genomes; biotechnological applications; translational genomics; new discoveries
(This special issue belongs to the Section Molecular Plant Sciences)
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