International Journal of Molecular Sciences

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Special Issue Information

Dear Colleagues,

Molecular imaging is an exciting field that can be defined as the visualization and/or measurement of biological or biochemical processes at cellular and molecular levels. It is performed in preclinical models and in living human subjects. By necessity, molecular imaging is multidisciplinary, applying synthetic and radiochemistry, molecular biology, (patho)physiology, and multiple imaging techniques. It leverages both endogenous and exogenous imaging probes to generate detectable signals. Molecular imaging techniques include optical and optoacoustic methods, ultrasound, molecular computed tomography, magnetic resonance imaging, and spectroscopy. Molecular imaging is used to diagnose diseases, assess treatment responses, and define the underlying pathophysiology of a disease process. To this end, molecular imaging has been used to non-invasively visualize aberrant tumor metabolism, bacterial infections, beta-cell mass and function, and adipocyte metabolism. This Special Issue focuses on developing and implementing molecular imaging strategies for research in obesity, diabetes, infectious diseases, and tumor metabolism. We welcome original research and review articles.

Prof. Dr. Orhan K. Öz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Related Special Issues

Published Papers (1 paper)

Review

19 pages, 2077 KiB

Open AccessReview

Advances in Imaging of Inflammation, Fibrosis, and Cancer in the Gastrointestinal Tract

by Kylene M. Harold, William M. MacCuaig, Jennifer Holter-Charkabarty, Kirsten Williams, Kaitlyn Hill, Alex X. Arreola, Malika Sekhri, Steven Carter, Jorge Gomez-Gutierrez, George Salem, Girish Mishra and Lacey R. McNally

Int. J. Mol. Sci. 2022, 23(24), 16109; https://doi.org/10.3390/ijms232416109 - 17 Dec 2022

Cited by 7 | Viewed by 2642

Abstract

Gastrointestinal disease is prevalent and broad, manifesting itself in a variety of ways, including inflammation, fibrosis, infection, and cancer. However, historically, diagnostic technologies have exhibited limitations, especially with regard to diagnostic uncertainty. Despite development of newly emerging technologies such as optoacoustic imaging, many recent advancements have focused on improving upon pre-existing modalities such as ultrasound, computed tomography, magnetic resonance imaging, and endoscopy. These advancements include utilization of machine learning models, biomarkers, new technological applications such as diffusion weighted imaging, and new techniques such as transrectal ultrasound. This review discusses assessment of disease processes using imaging strategies for the detection and monitoring of inflammation, fibrosis, and cancer in the context of gastrointestinal disease. Specifically, we include ulcerative colitis, Crohn’s disease, diverticulitis, celiac disease, graft vs. host disease, intestinal fibrosis, colorectal stricture, gastric cancer, and colorectal cancer. We address some of the most recent and promising advancements for improvement of gastrointestinal imaging, including unique discussions of such advancements with regard to imaging of fibrosis and differentiation between similar disease processes. Full article

(This article belongs to the Special Issue Molecular Imaging in Diabetes, Obesity, and Infections 3.0)

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