Cutting Edge Advances in Antitumor Properties of Natural Products
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 20 March 2026 | Viewed by 768
Special Issue Editors
Interests: natural product; cancer cells; apoptosis; cell cycle; signal transduction pathways; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Interests: onset of malignancy in breast and prostate cells; plant-based substances in oncology; signal transductional pathways; oxidative stress and apoptosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer is highly complex, as it consists of various types of cells, each with distinct characteristics. This diversity makes it difficult to treat using traditional therapies like chemotherapy and radiation, which attack both cancerous and healthy cells. Consequently, these treatments often cause severe side effects, including hematological toxicities and tissue damage. Despite significant progress in cancer therapy through the development of numerous drugs, controlling the disease remains challenging due to the ability of cancer cells to evolve and adapt. Over time, these adaptations can result in drug resistance. Natural products are gaining increasing attention in cancer research because of their potential to target multiple pathways involved in cancer simultaneously. These compounds can influence several critical processes such as cell proliferation, inflammation, apoptosis, angiogenesis, metastasis, and the capability to impact the tumor microenvironment. Therefore, they present several benefits, such as chemical diversity, minimal toxicity, the ability to overcome drug resistance, safety, and availability. Considering these advantages, bioactive molecules, either alone or in combination with traditional chemotherapeutic agents, could represent an effective alternative for cancer treatment. The aim of this Special Issue is to gather both original research and review articles that examine how natural products might influence tumor progression. The issue seeks to enhance our understanding of the mechanisms by which the natural bioactive molecules impact cancer growth and metastasis, providing valuable insights into their potential as therapeutic agents.
Dr. Francesca Giordano
Prof. Dr. Maria Luisa Panno
Guest Editors
Manuscript Submission Information
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Keywords
- natural product
- cancer
- cell signaling
- cell death and differentiation
- oxidative stress
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