Helicobacter: Infection, Diagnosis and Treatment 2.0

Dear Colleagues,

Helicobacter pylori is the most common infection in humans, with 50% of the world's population being affected. Chronic H. pylori infection is associated with increased risk for numerous diseases, including gastric cancer. The risk factors capable of influencing the outcome of a bacterial infection are a complex combination of host characteristics, bacterial virulence, and environmental factors. The human gastric mucosa appears to be the major site of infection, but recent findings demonstrate that H. pylori infection is also strongly associated with different extra-gastric diseases. Moreover, the anti-H. pylori therapeutic regimens currently available are encountering several problems due to the diffusion of multidrug resistance, highly correlated with specific geographical areas.

This Special Issue aims to highlight new contributions to the molecular mechanisms involved in H. pylori infection and host–pathogen interaction, so to understand the related pathologies and discover new anti-microbial agents.

Dr. Alessandra Tosco
Prof. Dr. Amalia Porta
Guest Editors

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