Research Progress in RNA-Binding Proteins 2.0

Dear Colleagues,

RNA-binding proteins (RBPs) are omnipresent in biology. Makers, breakers, modifiers, and sensors of RNAs unavoidably shift into the research focus in fields as different as molecular and cell biology, molecular genetics, infection and immunity, synthetic biology, and molecular medicine. They are also fascinating molecular objects with a stunning diversity of structures, RNA recognition modes, and activities. Standalone players or members of exuberant ribonucleoproteins, RBPs secure key housekeeping functions while also featuring in a number of accessory and regulatory roles. The last decade has seen a flurry of studies unravelling the genuine scope of RBP-mediated processes and molecular mechanisms. This Special Issue focuses on emerging molecular aspects of RBP biology and the new methods to approach them. This includes but is not limited to recent progress in the prediction, identification, structural characterization, and measurement of RNA–protein interactions, the biochemical behavior and activities of RBPs, novel and classical RBP classes, phase-separation and formation of biocondensates, RBP evolution, and design.

Dr. Alexandre Smirnov
Guest Editor

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