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Radiosensitizers in the Service of Radiotherapy: Drug Design, Development and Therapy

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Guest Editor
Laboratory of Biological Sensitizers, Department of Physical Chemistry, Faculty of Chemistry, University of Gdańsk, ul. Wita Stwosza 63, 80-308 Gdańsk, Poland
Interests: radiosensitizers; density functional theory; quantum chemical calculations; low-energy electrons; dissociative electron attachment; DNA damage; oxygen mimetics; modified nucleosides
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Special Issue Information

Dear Colleagues,

Radiotherapy is one of the most common forms of anticancer treatment and it could become even more efficient if enhanced by radio-sensitizing drugs. Such compounds may increase the impact of high-energy irradiation on radioresistant hypoxic cancer tissues. Supporting radiotherapy with safe and efficient radiosensitizers could be promising for numerous patients suffering from radioresistant types of cancer.

We would like to invite you to contribute to the Special Issue of the International Journal of Molecular Sciences, focusing on advances in radiosensitizers, titled “Radiosensitizers in the Service of Radiotherapy: Drug Design, Development and Therapy”. Original research articles on drug design, the synthesis of new radiosensitizers, and radiation chemistry; computational studies on the mechanisms of action of radiosensitizers; biological in vivo studies on cytotoxic properties and efficacy under irradiation; and review articles and short communications are welcome.

Dr. Lidia Chomicz-Mańka
Guest Editor

Manuscript Submission Information

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Keywords

  • radiosensitizers
  • radiotherapy
  • mechanistic studies
  • drug design
  • computational chemistry
  • radiation studies
  • cytotoxicity
  • hypoxia
  • radioresistance

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Published Papers

This special issue is now open for submission.
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