Metal Complexes: From Structural Characterization to Pharmacological Effects
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 82
Special Issue Editor
Interests: design of new metal complexes with biological activity (e.g., antibacterial, anticancer, and antidiabetic activity); synthesis, characterization; DNA binding and protein interaction studies; cytotoxicity studies; drug repositioning
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Special Issue Information
Dear Colleagues,
The therapeutic applications of metal-based drugs cover virtually every type of therapeutic agents: anticancer, antimicrobial, antiarthritic, antipsychotic, antihypertensive, antiviral, antiulcer, antacid, metalloenzyme-mimetic, radiotherapeutic, and metal chelating agents. Finding new metal-based agents is a significant and active area of research, driven by the need for new treatments to overcome limitations such as toxicity and resistance, such as in the case of platinum drugs or antimicrobial resistance (AMR). Medicinal inorganic chemistry is a multidisciplinary field that combines elements of chemistry (synthesis, reactivity), pharmacology (pharmacokinetics, toxicology), biochemistry (target, structure, conformational changes) and medicinal chemistry (therapeutics, pharmacodynamics, structure/activity relationships (SAR), aiming to develop new, more potent therapeutic agents with reduced adverse effects. In this regard, This Special Issue will present interdisciplinary studies on the synthesis, structural characterization, interaction with biological targets, mechanism of action, as well as the biological action and potential for therapeutic application, of some new metal complexes.
Prof. Dr. Valentina Uivarosi
Guest Editor
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Keywords
- metal complexes
- structural analysis
- medicinal inorganic chemistry
- metal–biomolecule interactions
- biological activity
- anticancer agents
- antimicrobial activity
- antiviruses activity
- antidiabetic activity
- pharmacological effects
- therapeutic applications
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