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Molecular Insight into Retinal Diseases: 2nd Edition

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 10

Special Issue Editors


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Guest Editor
1. Department of Chinese Medicine, School of Chinese Medicine, China Medical University, Taichung 404, Taiwan
2. Institute of Pharmacology, Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei 11221, Taiwan
3. Department of Ophthalmology, Shin Kong Hospital, Taipei 105, Taiwan
Interests: neuroprotection in retinal ischemia; vitreoretinal surgery
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Guest Editor
1. Machine Learning Division, Ophthalmic Research Laboratory, University of Adelaide, Adelaide, SA 5005 Australia
2. Department of Ophthalmology, Royal Adelaide Hospital, Adelaide, SA 5000, Australia
Interests: glaucoma; retinal cell biology; neuroprotection; ophthalmic epidemiology; translational ophthalmic
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Guest Editor
1. Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City, Taiwan
2. School of Medicine, Chang Gung University, Taoyuan City, Taiwan
Interests: uveitis; nonarteritic anterior ischemic optic neuropathy; vitreoretinal surgery
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Special Issue Information

Dear Colleagues,

Retinal vascular occlusion, normal tension glaucoma, diabetic retinopathy, and age-related macular degeneration (AMD) are associated with retinal ischemia and can threaten vision. The incidence rates of these diseases are as follows: 0.0018% for central retinal artery occlusion (CRAO); 4% for primary open-angle glaucoma (in urban areas); 2.9% for sight-threatening diabetic retinopathy (type 2 diabetes); and 0.36% for AMD (age ≥40).

The aim of this Special Issue is to evaluate the protective effects and underlying mechanisms of complementary medicine or therapies against retinal ischemia. Recent advancements in retinal research have addressed several subtopics: neuroprotection in retinal ischemia (e.g., anti-VEGF agents such as faricimab, protectants like modified cerebrolysin, acupuncture, stem cells, gene therapy, and retinal chips); femtosecond-assisted phacovitrectomy; Artisan lenses in IOL dislocation; Artiflex lenses in moderate myopia; exozymes in Harada disease with associated dry eye; and comparison of silicon oil versus scleral buckles in capsulotomized pseudophakic eyes with inferior break-induced inferior retinal detachment (RD).

In macular surgery, recent topics include the use of amniotic membranes or ILM flaps in macular holes with or without RD, as well as electrophysiological and pathological evaluations using techniques such as EOG, multifocal ERG, flash ERG, VEP, microperimetry, and OCT-A.

Please note that purely clinical studies are not suitable for submission to International Journal of Molecular Sciences (IJMS). However, clinical or preclinical model studies that incorporate biomolecular experiments are welcome.

Prof. Dr. Hsiaoming Chao
Prof. Dr. Robert Casson
Dr. Hsi-Kung Kuo
Guest Editors

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Keywords

  • faricimab
  • modified cerebrolysin
  • stem cells
  • gene therapy
  • retinal chip
  • femtosecond
  • artisan aphakia
  • artiflex
  • exozyme
  • silicon oil
  • amniotic membrane
  • EOG
  • multifocal ERG
  • flash ERG
  • VEP
  • microperimetry
  • OCT-A

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