Advances in Neurodegenerative Diseases Research and Therapy, Fourth Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 1309
Special Issue Editor
Interests: nerve growth factor; neurotrophins; Alzheimer’s disease; therapy; encapsulated cell biodelivery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Degenerative diseases of the nervous system affect millions of people worldwide and remain associated with limited therapeutic options, in part because the blood–brain barrier restricts the passage of most drug candidates into the brain tissue. 'Neurodegenerative disease' is commonly used as an umbrella term encompassing a range of debilitating conditions that affect the brain, including Alzheimer's disease, Parkinson's disease, and Huntington's disease, among others. Historically, research in this field has focused primarily on neuronal degeneration as the primary cause of these diseases. However, accumulating evidence now highlights the critical role of glial cells in maintaining physiological neural function and contributing to disease onset and progression.
Although neurodegenerative diseases exhibit distinct pathological hallmarks and clinical symptoms, they share common molecular pathways, including gliosis, proteostasis, inflammation, and metabolic alterations. A deeper understanding of the molecular changes that occur during disease development and progression is, therefore, essential for the identification and design of effective therapeutic interventions.
This Special Issue, ‘Advances in Neurodegenerative Diseases Research and Therapy, Fourth Edition’, continues to invite original research articles and reviews that provide updated insights into the molecular mechanisms underlying neurodegenerative diseases. Particular emphasis will be placed on the development of clinically relevant therapeutic strategies, including optimization studies, clinical efficacy studies, biomarker evaluations, drug delivery approaches, and more.
Dr. Sumonto Mitra
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
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Keywords
- neurodegenerative diseases
- therapy
- molecular mechanisms
- neuron
- astrocytes
- microglia
- inflammation
- brain
- drug delivery
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Related Special Issues
- Advances in Neurodegenerative Diseases Research and Therapy—Third Edition in International Journal of Molecular Sciences (9 articles)
- Advances in Neurodegenerative Diseases Research and Therapy 2.0 in International Journal of Molecular Sciences (8 articles)
- Advances in Neurodegenerative Diseases Research and Therapy in International Journal of Molecular Sciences (6 articles)
