Anesthetic and Sedative Actions on Nervous System Development
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 1885
Special Issue Editor
Special Issue Information
Dear Colleagues,
Studies from animal models including rodents and nonhuman primates have demonstrated that early developmental exposure to general anesthetic and sedative agents alters the development of the nervous system, and that these changes may have lasting, harmful effects. Investigators have demonstrated deficits in learning and memory as well as in affective behaviors, and a wide array of pathologic consequences including cell death, impaired neurogenesis, disruptions in axon and dendrite formation, loss of synapses, and aberrations in glial cell development, has been documented. The clinical significance of these findings in human pediatric patients remains unclear and thus an area of concern that requires further research in order to ensure that anesthesiologists and critical care physicians can provide the highest level of safety to vulnerable patients.
In this Special Edition, we are soliciting manuscripts ranging from original research to review articles that provide novel and timely insights into how anesthetics and sedatives act on nervous system development. Investigations that range from basic science to translation or clinical topics will be considered, with particular interest in newly discovered targets, novel phenotypes, and risk factors for vulnerability.
Since IJMS is a journal of molecular science, thus pure clinical studies will not be suitable for our journal. But clinical submissions with biomolecular experiments are welcomed.
Dr. Cyrus David Mintz
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
