Latest Insights into Glycobiology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 210
Special Issue Editors
Interests: liquid-chromatography; mass-spectrometry; glycosylation; biomarker discovery
2. Samsung Advanced Institute of Health Science and Technology (SAIHST), Sungkyunkwan University, Seoul 06351, Republic of Korea
Interests: glycobiology; sialobiology; sialyltransferase; N-glycan; O-glycan; glycolipid; sphingolipid; glycoprotein; surface sugar; ganglioside; sialic acid; sialyl Le antigen; lectin; galectin; siglec; ER-Golgi glyosylation; sugar–receptor interaction; innate immune; xenotransplantation; cell–cell interaction
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Special Issue Information
Dear Colleagues,
Glycobiology, the study of glycans and their roles in biological systems, is experiencing rapid advancements, offering profound insights into health and disease. Recent discoveries highlight the immense structural diversity of glycans and their pivotal functions in cell–cell communication, immune modulation, and molecular recognition. Technological innovations, including high-resolution mass spectrometry and glycan microarrays, have enhanced our ability to analyze glycan structures, driving significant progress in the field. Abnormal glycosylation patterns are increasingly linked to various diseases, such as cancer, neurodegenerative disorders, and infectious diseases, providing new targets for therapeutic interventions and biomarker discovery. Glycans are also recognized for their critical role in modulating immune responses, influencing pathogen recognition and inflammation, thus offering novel pathways for immunotherapy development. Advances in glycoengineering are facilitating the creation of glycoproteins with improved therapeutic properties, which is pivotal in the development of biopharmaceuticals and vaccines. Additionally, glycans are key mediators in host–microbe interactions, essential for understanding microbial colonization and immune evasion. The field of glycobiology is benefiting from interdisciplinary collaborations, integrating genomics, proteomics, and bioinformatics to deepen our understanding of glycan functions. These insights are paving the way for innovative applications in medicine and biotechnology, highlighting the expanding role of glycobiology in addressing complex biological challenges.
Dr. Csaba Váradi
Prof. Dr. Cheorl-Ho Kim
Guest Editors
Manuscript Submission Information
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Keywords
- glycosylation
- biomarkers
- separation techniques
- mass spectrometry
- multivariate data analysis
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