Innovative Approaches in Personalized Medicine: Cancer, Inherited Diseases, and Beyond
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 10 November 2025 | Viewed by 48
Special Issue Editor
Special Issue Information
Dear Colleagues,
Recent advancements in diagnostic technologies—encompassing both germline and somatic genetic analysis—have led to the identification of novel molecular targets, unlocking new therapeutic opportunities not only for oncological conditions but also for rare hereditary diseases. Additionally, pharmacogenetics has revealed significant variability in how individuals metabolize medications, underscoring the need for personalized dosing strategies. However, this crucial information remains unavailable for many patients due to the lack of simple, widely accessible diagnostic tests. These tests could reduce healthcare costs in the long run while protecting patients from adverse drug reactions. In parallel, current early detection programs primarily rely on age as the sole risk factor, overlooking the influence of genetic and non-genetic factors on an individual’s disease susceptibility. The development of broad, reliable tools for personalized risk assessment could lead to tailored prevention strategies, enabling more effective and less harmful early interventions. Ultimately, the goal in personalized medicine is to match each patient with the most effective therapies and surveillance strategies, ensuring optimized treatment outcomes and reducing side effects. Continued research including genomes for rare germline and somatic disorders, as well as polygenic factors for common entities is essential in advancing these diagnostic and therapeutic approaches, improving healthcare delivery and patient well-being.
Therefore, we invite submissions of original research articles, reviews, and communications focusing on molecular aspects of personalized medicine.
Dr. Julia Hentschel
Guest Editor
Manuscript Submission Information
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Keywords
- personalized medicine
- hereditary diseases
- pharmacogenomics
- proteomics
- polygenic factors
- molecular pathology
- therapeutic approaches
- biomarkers
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