Current Advances in Soft Tissue and Bone Sarcoma 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (28 February 2020) | Viewed by 4107
Special Issue Editors
2. Department of Medical Oncology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan
Interests: new antineoplastic drugs; resistance to molecular target drug; biomarkers of cancer; bone metastases of cancer; sarcomas
Special Issues, Collections and Topics in MDPI journals
Interests: medicine and surgery; cell biology; osteosarcoma
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to announced the continuation of our Special Issue “Current Advances in Soft Tissue and Bone Sarcoma” with a second edition.
The molecular basis of soft tissue and bone sarcoma has received considerable attention during the last decade. However, clinical outcomes continue to be dismal and have landed this group of cancers among the “most pressing” for development of new, effective therapies. The main barrier to successfully treating many sarcoma types is the lack of robust prognostic markers and the absence of effective therapeutics. The complex biology and tumor heterogeneity of sarcomas make it challenging to identify and evaluate new therapeutic targets and agents. These challenges are also compounded by the orphan disease status.
In this Special Issue, original studies and review articles on the diagnosis, pathobiology, and novel therapies of soft tissue and bone sarcoma, including genetics, epigenetics, immunotherapies, epidemiology, signaling pathways, and preclinical models, will be published. The issue will also cover reports on current treatments and novel combination therapies, including immunotherapies, providing novel mechanistic insights that may impact clinical outcomes.
Prof. Dr. Shunji Takahashi
Prof. Dr. Eugenie S. Kleinerman
Guest Editors
Manuscript Submission Information
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Keywords
- Soft tissue sarcoma
- Osteosarcoma
- Pathobiology
- Genetics
- Current treatments
- Diagnosis
- Outcomes and preclinical models
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