Molecular and Cellular Mechanisms Underlying Kidney Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 2
Special Issue Editor
Special Issue Information
Dear Colleagues,
Acute kidney injury (AKI) remains a complex and life-threatening condition associated with high morbidity and mortality. Despite advances in clinical care, there are still no effective pharmacological treatments available. Understanding the underlying mechanisms of AKI is essential for developing targeted and effective therapies. This Special Issue aims to highlight recent progress in the mechanistic understanding of AKI and its translation into potential treatments. We particularly welcome studies utilizing experimental models to investigate various causes of AKI, including ischemia-reperfusion injury, sepsis, nephrotoxins, and rhabdomyolysis-induced acute kidney injury (RIAKI). We encourage original research and comprehensive review articles that elucidate cellular and molecular pathways involved in AKI and assess potential pharmacologic interventions. This Special Issue seeks to bring together nephrologists, researchers, and clinicians to share novel insights and experimental evidence that can bridge the gap between theoretical science and clinical application. By deepening our understanding of AKI mechanisms, we can pave the way toward the development of effective therapeutic strategies to prevent and treat AKI.
Dr. Dong-Jun Park
Guest Editor
Manuscript Submission Information
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Keywords
- acute kidney injury
- molecular mechanisms
- therapeutic agents
- experimental model
- pathophysiology
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