Recent Advances in Antitumor Agents from Natural Source
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 750
Special Issue Editor
Special Issue Information
Dear Colleagues,
The relentless pursuit of effective cancer treatments continues to drive significant scientific research into the potential of natural sources. This Special Edition explores recent discoveries of anticancer agents originating from diverse biological realms, including terrestrial flora, microbial communities, and marine ecosystems. We invite you to explore the multifaceted mechanisms through which these natural compounds exert their effects. These mechanisms range from the direct induction of programmed cell death and the disruption of tumor blood vessel formation to the critical modulation of the complex tumor microenvironment and the circumvention of drug resistance. This Special Issue will determine the promise of these substantial natural leads and significant hurdles that continue to prevent their clinical application. These challenges encompass the intricacies of compound isolation, purification, structural elucidation, and the optimization of pharmacokinetic and pharmacodynamic properties. In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: medicinal plants extracts, isolated compounds, natural molecules obtained from synthesis, and pharmacological and toxicological assays for cancer. Moreover, we underscore the particular importance of employing sustainable harvesting practices and prioritizing the conservation of biodiversity to ensure the long-term availability of these invaluable resources for future drug discovery endeavors.
This Special Issue is supervised by Dr. Fabio Ferreira Perazzo（University of São Paulo) and assisted by Dr. Renato Farina Menegon（University of São Paulo).
Dr. Fábio Ferreira Perazzo
Guest Editor
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Keywords
- natural products
- cancer
- medicinal plants
- phytochemistry
- fermented compounds
- isolated compounds
- tumor
- in vitro
- in vivo
- clinical trials
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