The Molecular Brain and Its Health

    Studies to date indicate that the efficacious curation of brain damage, in particular neurodegeneration due to brain disease and brain injury, appears to depend on the multifaceted effects of the individual promising agents in question. To list the targets of such modulatory effects: inflammatory and/or immune response mechanisms of microglia cells; interactions between astrocytes and neurons serving to maintain the homeostatic equilibrium of the brain; oligodendritic functions serving to maintain efficient signaling from neuron to neuron; endothelial cell states underlying proper blood–brain barrier function, and even brain vascular function; programmed cell death pathways of the various cell types; regulation of stem cell activity; regeneration and wound healing.   
    This Special Issue on “The Molecular Brain and its Health” aims to gather papers addressing the abovementioned topics, in particular the underlying molecular biological mechanisms affected by the curative agents in question. Obviously, each stipulated effect in and by itself presents its own complexity. Thus, we hope that this Special Issue can bring together these singular molecular biological mechanisms. As research progresses, computational approaches also integrate the various functional pathways that will become important to conceive.

Dr. Leo Veenman
Guest Editor

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