Unique Properties of Glial Cells in the CNS
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (20 December 2024) | Viewed by 1416
Special Issue Editor
Special Issue Information
Dear Colleagues,
Emerging evidence suggests that glial cells, such as astrocytes, microglia, oligodendrocytes, and their precursor cells, are not simply a group of cells filling brain tissue, as previously thought, but a heterogeneous multipotent population with different properties in different brain regions. Recently, many reports have emerged showing that these glial cells have roles and unique functions that they were previously thought not to be absent. Specifically, some glial cells appear to be electro-sensitive, have phagocytic functions, support the integrity of the blood–brain barrier, form synapses with neurons, and induce, mediate, or inhibit CNS inflammation. However, compared to neurons, many aspects of glial cells remain unexplored. This Special Issue will, therefore, focus on the “unique properties” of glial cells, discussing them beyond their previously well-known roles and their contribution to CNS homeostasis, and outline how functional alterations of glial cells play an important role in many neurological disorders.
Dr. Hisashi Shirakawa
Guest Editor
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Keywords
- glial cells
- astrocytes
- microglia
- oligodendrocytes and their precursor cells
- unique properties
- neurological disorders
- CNS inflammation
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