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Coordination Complexes: From Molecular Design to Functional Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Physical Chemistry and Chemical Physics".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 5354

Special Issue Editor

1. Natural Compounds and Organic Synthesis Department, MIGAL—Galilee Research Institute, Kiryat Shmona 11016, Israel
2. Biotechnology Department, Tel-Hai Academic College, Upper Galilee 9977, Qiryat Shemona 1220800, Israel
Interests: organic synthesis; biochemistry; microencapsulation; analytical chemistry

Special Issue Information

Dear Colleagues,

This Special Issue focuses on the design, synthesis, and comprehensive characterization of coordination complexes, highlighting their transformation into functional materials with a wide array of applications. Special attention is given to elucidating the structure–property relationships that dictate the performance of these complexes in diverse fields such as catalysis, chemical sensing, magnetism, photophysics, optoelectronics, energy conversion and storage, and biomedical technologies.

Contributions that explore innovative ligand frameworks, novel coordination geometries, and advanced metal–ligand interactions that enable the fine-tuning of physicochemical properties are welcome. Studies leveraging state-of-the-art synthetic approaches, spectroscopic and structural techniques, and computational modeling to gain deeper insights into complex behavior are particularly encouraged.

In bridging the gap between fundamental coordination chemistry and practical implementation, this Special Issue aims to showcase the pivotal role of coordination compounds in addressing current scientific and technological challenges. Both original research articles and comprehensive review papers are invited to present the latest advancements and future perspectives in this rapidly evolving field.

Dr. Sanaa Musa
Guest Editor

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Keywords

  • coordination complexes
  • organometallic complexes
  • functional materials
  • metal–ligand interactions
  • homogenous catalysis
  • sensing
  • magnetic materials
  • ligand tunability

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Published Papers (2 papers)

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Research

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15 pages, 4410 KiB  
Article
Synthesis, Structure, and Properties of a Copper(II) Binuclear Complex Based on Trifluoromethyl Containing Bis(pyrazolyl)hydrazone
by Olga G. Shakirova, Tatiana D. Morozova, Yulia S. Kudyakova, Denis N. Bazhin, Natalia V. Kuratieva, Lyubov S. Klyushova, Alexander N. Lavrov and Lyudmila G. Lavrenova
Int. J. Mol. Sci. 2024, 25(17), 9414; https://doi.org/10.3390/ijms25179414 - 30 Aug 2024
Cited by 2 | Viewed by 1512
Abstract
A new complex of copper(II) with methyl-5-(trifluoromethyl)pyrazol-3-yl-ketazine (H2L) was synthesized with the composition [Cu2L2]∙C2H5OH (1). Recrystallization of the sample from DMSO yielded a single crystal of the composition [Cu2L [...] Read more.
A new complex of copper(II) with methyl-5-(trifluoromethyl)pyrazol-3-yl-ketazine (H2L) was synthesized with the composition [Cu2L2]∙C2H5OH (1). Recrystallization of the sample from DMSO yielded a single crystal of the composition [Cu2L2((CH3)2SO)] (2). The coordination compounds were studied by single-crystal X-ray diffraction analysis, IR spectroscopy, and static magnetic susceptibility method. The data obtained indicate that the polydentate ligand is coordinated by both acyclic nitrogen and heterocyclic nitrogen atoms. The cytotoxic activity of the ligand and complex 1 was investigated on human cell lines MCF7 (breast adenocarcinoma), Hep2 (laryngeal carcinoma), A549 (lung carcinoma), HepG2 (hepatocellular carcinoma), and MRC5 (non-tumor lung fibroblasts). The complex was shown to have a pronounced dose-dependent cytotoxicity towards these cell lines with LC50 values in the range of 0.18–4.03 μM. Full article
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Review

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30 pages, 6125 KiB  
Review
Advances in Chiral Pincer Complexes: Insights and Applications in Catalytic Asymmetric Reactions
by Sanaa Musa, Yuval Peretz and Gil Dinnar
Int. J. Mol. Sci. 2024, 25(19), 10344; https://doi.org/10.3390/ijms251910344 - 26 Sep 2024
Cited by 1 | Viewed by 2215
Abstract
Chiral pincer complexes, characterized by their rigid tridentate coordination framework, have emerged as powerful catalysts in asymmetric synthesis. This review provides a comprehensive overview of recent advancements in the development of chiral pincer-type ligands and their corresponding transition metal complexes. We highlight the [...] Read more.
Chiral pincer complexes, characterized by their rigid tridentate coordination framework, have emerged as powerful catalysts in asymmetric synthesis. This review provides a comprehensive overview of recent advancements in the development of chiral pincer-type ligands and their corresponding transition metal complexes. We highlight the latest progress in their application across a range of catalytic asymmetric reactions, including the (transfer) hydrogenation of polar and non-polar bonds, hydrophosphination, alkynylation, Friedel-Crafts reactions, enantioselective reductive cyclization of alkynyl-tethered cyclohexadienones, enantioselective hydrosilylation, as well as Aza–Morita–Baylis–Hillman reactions. The structural rigidity and tunability of chiral pincer complexes enable precise control over stereoselectivity, resulting in high enantioselectivity and efficiency in complex molecular transformations. As the field advances, innovations in ligand design and the exploration of new metal centers are expected to expand the scope and utility of these catalysts, bearing significant implications for the synthesis of enantioenriched compounds in pharmaceuticals, materials science, and beyond. Full article
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