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Formation of Chiral Supramolecular Assemblies

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Physical Chemistry and Chemical Physics".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 78

Special Issue Editor


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Guest Editor
Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences in Lodz, Sienkiewicza 112, 90-363 Lodz, Poland
Interests: organic synthesis; stereochemistry; asymmetric synthesis; chiral (organo)catalysts; conductive organic polymers; organic electronics; flame retardants; organophosphorus; organosulfur and organoselenium chemistry; drug polymorphs

Special Issue Information

Dear Colleagues,

Supramolecular systems are defined as well-organized molecular assemblies composed of multiple components that maintain their self-organized architecture through non-covalent interactions, including electrostatic forces, π–π stacking interactions, hydrogen bonding, and metal–ligand coordination.

Chirality in chemical architectures is observed at the supramolecular level, as seen in the helical chirality of double-stranded DNA. Chiral molecular assemblies are exemplified by both low- and high-molecular-weight compounds, particularly chiral biomolecules such as enzymes, proteins, and nucleic acid strands, which are well-known for their biomedical applications. Additionally, examples include inclusion complexes, crown ethers, and cage-like catalysts that exhibit host–guest binding behavior, important for molecular recognition. Furthermore, chiral nanostructures and chiral polymers have been developed for their potential applications as functional materials in material sciences and organic synthesis. This Special Issue will present recent advances in the field of supramolecular chemistry regarding the self-organization of chiral molecules into well-defined systems.

Research areas for this Special Issue may include (but are not limited to) the following topics:

  • Synthesis, preparations of chiral structures for supramolecular assemblies and their applications;
  • The nature of supramolecular interactions;
  • The study of the host–guest behavior;
  • The significance of chiral supramolecular assemblies and supramolecules;
  • The self-assembly of achiral and chiral molecules;
  • Aspects of stereochemistry within these architectures, including chiral and molecular recognition;
  • The role of supramolecules in biocatalysis;
  • The function of enzymes in organic and/or asymmetric synthesis;
  • The physicochemical properties of the chiral supramolecular assembies.

Researchers working in this field are invited to submit original research papers and review articles to this Special Issue.

We look forward to receiving your contributions.

Dr. Dorota Krasowska
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chiral macromolecules
  • supramolecular assemblies
  • helical chirality
  • molecular recognition
  • host–guest systems
  • self-assembly
  • self-organization
  • biomolecules
  • non-bonding interactions

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Published Papers

This special issue is now open for submission.
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