Molecular Therapy for Heart Failure
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 March 2024) | Viewed by 490
Special Issue Editor
2. Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Wroclaw University of Environmental and Life Sciences, 50-375 Wrocław, Poland
Interests: veterinary cardiology; echocardiography; physiology; pathological anatomy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Heart failure has been one of the most common causes of death globally for many years, which is why new, more effective therapeutic strategies are constantly being sought. One of the most promising is gene therapy. Contrary to earlier concerns, the clinical safety and effectiveness of gene therapy have been demonstrated, among others, by transdermal administration of an adenoviral viral vector expressing sarc-endoplasmic reticulum calcium ATPase—SERCA2a—in the recently successfully completed Phase II of the Calcium Regulation by the Heart Disease Study (CUPID). The introduction of gene therapy allows the manipulation of molecular targets that are currently not amenable to pharmacological modulation. Molecular gene therapy is an extremely dynamically developing field of medicine, in which many outstanding research teams are involved. We encourage you to share your achievements and doubts about gene therapy for heart disease.
Prof. Dr. Urszula Pasławska
Guest Editor
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Keywords
- heart failure
- gene therapy
- heart disease
- coronary artery disease
- high blood pressure
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