Obesity and Arterial Hypertensionis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 12054
Special Issue Editor
Interests: platelets; animal physiology; ontogenesis; cardiology; arterial hypertension; metabolic disorders
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues，
The world is currently faced with obesity, growing as a disease across all demographics of the human population. This is manifested by an increase in body weight due to an excess amount of adipose tissue and a violation of metabolic processes throughout the body. Very often, abdominal obesity contributes to the development of various pathologies, among which arterial hypertension occurs most often. This combination is capable of leading to various vascular disorders that cause decreased work ability, disability and life expectancy.
Numerous studies have shown that obesity and arterial hypertension can provoke one another and aggravate the course of their development. It has been shown that an important role is played by the development of oxidative stress, damage to the vascular endothelium, disruption of receptor apparatus, and sometimes the development of insulin resistance. At the same time, the subtle molecular mechanisms of the development of obesity and arterial hypertension are still in the plane of scientific discussion. Their disclosure will allow for a new look at the pathogenesis of the isolated and combined occurrence of arterial hypertension and obesity. This can help to further improve approaches to the prevention and treatment of obesity and arterial hypertension.
Existing approaches to the treatment of obesity and arterial hypertension are currently being developed in detail. The possibilities of various options for correcting the dietary regimen and the effect of physical activity have been studied, as have the various schemes of drug exposure, with a large number of drugs being known. At the same time, due to insufficient knowledge of the molecular mechanisms of the formation of obesity and arterial hypertension and an incomplete understanding of the effect of the treatment used on these mechanisms, the problem of these two diseases is still very urgent. This Special Issue attempts to present the latest advances in obesity and hypertension research. In this regard, clinical observations and experimental studies performed at the molecular level on the issue of this issue are encouraged.
Prof. Dr. Ilya Nikolaevich Medvedev
Guest Editor
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Keywords
- obesity
- arterial hypertension
- vascular wall
- treatment with organoprotection
- prevention of thrombosis
- non-drug treatment
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