Gene Transfer in Microorganisms and Human Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 1870
Special Issue Editors
Interests: gene therapy; viral vectors; non-viral vectors; biomaterials; nanomaterials; polymers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The delivery of genes and drugs into cells has increasingly attracted attention for the generation of genetically engineered cells. Successful drug delivery will have enormous academic, clinical, and practical impacts on gene therapy, cell and molecular biology, pharmaceutical and food industries, and bio-production. The major aim of gene therapy is to deliver genetic materials into cells effectively, genetically modifying and repairing cell functions with the possibility of inducing therapeutic healing of disease. The genetic material includes DNA, RNA, antisense, decoy DNA, and ribozymes. The aim is that the appropriate transfection would allow diseased cells to return to a healthy condition. The genetic manipulation is often manifested in the mechanisms of intracellular actions of genes and proteins, and may play an important role in making clear the key genes associated with various diseases. Based on fundamental and scientific knowledge, the delivery technology of genetic material should be applicable to producing various proteins of pharmaceutical value (e.g. cytokines, growth factors, and antibodies) and also to producing seeds resistant to harmful insects and cold weather damage. This implies that the cells might be enhanced to produce valuable pharmaceutical and food products.
Prof. Dr. Hossein Hosseinkhani
Prof. Dr. Avi Domb
Guest Editors
Manuscript Submission Information
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Keywords
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in vitro transfection
- gene delivery
- enhanced gene expression
- polymers
- biomaterials
- nanoparticles
- drug delivery
