Signalling Pathways in Metabolic Diseases and Cancers

Dear Colleagues,

Cellular signaling pathways play a crucial role in cellular communication and adaptation to the everchanging surrounding environment, ultimately governing key fate decisions such as cell death, survival, division, or senescence. Cellular signaling processes are elicited by a variety of extracellular and intracellular inducers, such as growth factors, nutrients, or stress and damage stimuli. Likewise, the transmission of information on activated signaling pathways can rely on a plethora of signaling mediators. Moreover, many of these pathways are connected to form signaling networks to ensure the right timing and termination of cell responses. Notably, the dysregulation of signaling pathways has been implicated in the pathogenesis of several diseases, including cancer, inflammation, and metabolic disorders.

We therefore welcome original papers that report novel research findings and results on different aspects of cellular signaling, with special attention paid to novel regulators of pro-survival/pro-apoptotic signaling cascades; advances in targeted therapeutic strategies to manipulate signaling cascades, such as immunological therapies and so on; and the investigation of dysregulated molecular mechanisms underlying several metabolic and immunological diseases and tumors.

This Special Issue is supervised by Dr. Bossio and assisted by Dr. Gallo and Dr. Palummo.

Dr. Sabrina Bossio
Guest Editor

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