Advances in Enzyme Inhibitors: Mechanisms, Applications, and Future Perspectives

Dear Colleagues,

Enzyme inhibitors are of the utmost importance in various domains, such as drug discovery, agriculture, and industrial applications. This Special Issue offers a comprehensive overview of recent advancements in enzyme inhibitors, encompassing their diverse mechanisms, applications, and prospects. Enzyme inhibition is a vital strategy in drug design and development, particularly for the treatment of diseases like cancer, infectious diseases, and metabolic disorders. This issue highlights innovative approaches to designing and optimizing enzyme inhibitors, such as structure-based drug design, fragment-based drug discovery, and computational methods. Additionally, this Special Issue explores the broad spectrum of applications of enzyme inhibitors beyond traditional drug therapy, including their utilization in agriculture and industrial processes to produce fine chemicals, biofuels, and pharmaceutical intermediates. Topics of interest include the development of novel enzyme targets, innovative drug delivery systems, and strategies to overcome resistance mechanisms. Authors are encouraged to present original research, reviews, and perspectives that showcase the diverse applications and potential of enzyme inhibitors in these fields. This Special Issue serves as a platform for researchers and experts in the field of enzyme inhibitors to share their latest findings, foster interdisciplinary collaborations, and contribute to the advancement of knowledge in this critical area of science and technology. Potential authors are invited to submit their contributions that address any aspect of enzyme inhibition with an emphasis on innovation, relevance, and impact.

Dr. Clemente Capasso
Dr. Valeria Pittalà
Guest Editors

Manuscript Submission Information

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• enzyme inhibitors
• drug design
• drug discovery
• drug therapy
• resistance mechanisms
• cancer
• drug delivery systems
• biocatalysts
• enzymes in industrial applications