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Liquid-Phase Electron Microscopy in Biological Applications and Material Sciences

This special issue belongs to the section “Molecular Biology“.

Special Issue Information

Dear Colleagues,

The high-resolution observation of biological specimens and material phenomena in liquid is a fascinating field that has a huge frontier. Recent advances in the manufacture of tough electron-transparent films have realized the stable observation of samples by electron microscopy, delivering significant findings in many research fields. This Special Issue will include results from bio-related fields and material sciences and consider the future direction of the electron microscopy of specimens in liquid. The observation of biological samples, the nano-structures of materials and their dynamics, are of high interest for this Special Issue. We also aim to address experimental and technical challenges that have to be met in order to use an instrument that requires a vacuum environment to image a specimen in liquid. We envisage reports of novel specimen preparation methods and adapted instrumentation, e.g., the development of new specimen holders that include a micro-fluidics chamber and of electro-chemical holders that allow phenomena to be clarified at a molecular level and, of course, the modification of scanning, transmission and scanning transmission electron microscopes (TEM, STEM, and SEM) for their use. The study of metal sedimentation and electrochemical reactions are also of high interest for this Special Issue. Contributions relevant to basic biology, applied biology, and diagnostic research (because they exploit the speed of liquid-phase electron microscopy) are encouraged. Partial clinical research and survey studies are not within the scope of this Special Issue.

Dr. Chikara Sato
Guest Editor

Manuscript Submission Information

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Keywords

  • Environmental cell
  • Immuno-electron microscopy
  • Cell signaling
  • Comparative anatomy
  • Diagnosis
  • Molecular recognition
  • Molecular complexes
  • Electro-chemistry
  • Liquid phase synthesis
  • Metal sedimentation

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Int. J. Mol. Sci. - ISSN 1422-0067