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Redox, Antioxidant and Mitochondrial Signaling

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 20 November 2025 | Viewed by 54

Special Issue Editor


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Guest Editor
Department of Pharmacology and Physiology, Georgetown University Medical Center, 3900 Reservoir Road NW, Washington, DC 20057, USA
Interests: antioxidants; cell signaling; oxygen; reactive oxygen species; redox; signal transduction
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Since Rebeca Gerschman and Daniel Gilbert proposed the role of oxygen free radicals in oxygen toxicity in 1954, reactive oxygen species (ROS) have been known to cause damage to biological systems. However, in early 1990, a paradigm shift occurred and the role of ROS as mediators of cell signaling emerged. Consequently, antioxidants that regulate the levels of ROS as well as ROS generators such as the mitochondria are now thought to participate in ROS-defining cell signaling in a complex biological process called redox signaling. 

In this Special Issue, the advancements in the last 70 years in the understanding of the roles of ROS as damage-causing species as well as regulators of physiological processes, particularly in the field of cell signaling, are discussed.

Prof. Dr. Yuichiro J. Suzuki
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oxygen
  • reactive oxygen species
  • antioxidants
  • signal transduction

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Published Papers

This special issue is now open for submission.
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