Special Issue "Cytokines/Chemokines in Cancer Metastasis"
Deadline for manuscript submissions: closed (15 February 2021) | Viewed by 63795
Interests: chemokines; cytokines; microRNAs; noncoding RNAs; breast cancer; lung cancer; brain metastasis; metastasis; experimental therapeutics; nanotechnology
Special Issues, Collections and Topics in MDPI journals
Special Issue in International Journal of Molecular Sciences: Cytokines/Chemokines in Cancer Metastasis 2.0
Special Issue in International Journal of Molecular Sciences: Non-coding RNAs and Novel Therapeutic Targets in Human Cancers
The survival of the majority of patients with solid tumors has increased due to advances in diagnosis, imaging, surgery, and therapy. However, cancer metastasis is the leading cause of cancer-related deaths. There is an urgent need to understand the biology of metastasis for the development of novel preventive/therapeutic approaches for controlling metastasis to distant organs. Cancer cells release cytokines or chemokines that will communicate through their receptors present on stromal (paracrine mechanism) and cancer cells (autocrine mechanism). An altered expression profile of chemokines/cytokines regulates angiogenesis, proliferation, and metastasis at various stages in the solid tumors. It has been shown that blocking chemokines/cytokines or their cognate receptors plays a significant role in controlling cancer progression/metastasis. In addition, cytokines and chemokines can be used to improve the response of chimeric antigen receptor (CAR)-T cells against solid malignancies. The papers in the current Special Issue will cover all the topics of chemokines/cytokines and their role in the tumor microenvironment and blocking strategies of these axes as a monotherapy and combination therapies for the prevention of metastasis.
Dr. Mohd W. Nasser
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Chemokine receptors
- Cytokine receptors
- CAR-T cell therapy
- Cytokine therapy
- Chemokine therapy
- Vascular co-option
- Tumor-associated macrophages
- Myeloid-derived suppressor cells
- Regulatory T-cells (Treg)
- Cytotoxic T-cells