Molecular Research of Cancer Metabolism and Biomarkers
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 July 2025 | Viewed by 1387
Special Issue Editor
Interests: translational oncology; resistance to therapy; secretome signaling; microRNAs; cell transformation; tumor microenvironment
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
It is well established that metabolic reprogramming is a major feature of neoplastic transformation and progression. Metabolic reprogramming involves complex pathway remodeling and multifaceted interactions between cancer cells and the TME, thereby influencing resistance to chemotherapy and biologicals, including immunotherapy. Despite this growing body of knowledge, the extent to which metabolic remodeling confers protumorigenic features in clinically relevant settings still needs to be elucidated and is critical for the development of metabolic modulators that can attenuate cancer progression in vivo. On the other hand, gaining knowledge about these processes goes hand in hand with the identification of prognostic and diagnostic biomarkers. These efforts clearly necessitate multidisciplinary approaches and a multifaceted omics approach.
We invite all colleagues to contribute to this interesting discussion led by Dr. Mario Cioce, who will be assisted by our Topical Advisory Panel Member Dr. Surbhi Chouhan (Department of Molecular Biology UT Southwestern Medical Center 5323 Harry Hines Blvd Dallas).
Dr. Mario Cioce
Guest Editor
Manuscript Submission Information
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Keywords
- metabolic reprogramming
- tumor microenvironment (TME)
- resistance
- metabolic modulator
- multidisciplinary omics approach
- cancer metabolism
- biomarkers
- cancer stem cells
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