Recent Developments in Obesity: Metabolism, Pathophysiology and Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 1040
Special Issue Editor
Special Issue Information
Dear Colleagues,
Recent studies have shed light on the complex metabolic pathways involved in obesity. Key findings include the identification of novel adipokines that influence insulin sensitivity and lipid metabolism. Studies have demonstrated that pro-inflammatory cytokines contribute to insulin resistance and adipose tissue remodeling. Pathophysiological insights reveal the contribution of chronic inflammation and hypothalamic–pituitary–adrenal axis dysregulation to obesity. Additionally, the interplay between the gut microbiota and host metabolism has been explored, revealing potential therapeutic targets for obesity management. Recent clinical trials have evaluated the efficacy of new anti-obesity drugs, such as GLP-1 receptor agonists. In addition, lifestyle interventions, including personalized nutrition and physical activity programs, have been refined to enhance adherence and long-term success. These advancements offer new avenues for effective obesity management and highlight the importance of a multidisciplinary approach to tackle this global health challenge.
Original research papers and comprehensive, up-to-date review articles are all welcome.
Prof. Dr. Peteris Tretjakovs
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- obesity
- adipokines
- insulin sensitivity
- lipid metabolism
- pro-inflammatory cytokines
- gut microbiota
- GLP-1 receptor agonists
- personalized nutrition
- lifestyle interventions
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
