Insights into Multiple Myeloma: Immune Microenvironment, Disease Mechanisms, and Therapeutic Innovations
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 1
Special Issue Editor
Interests: cancer biology; gene regulation; cancer cells microarray; gene mapping; multiple myeloma; leukemia; cell culture; gene expression; genome editing
Special Issue Information
Dear Colleagues,
Multiple myeloma (MM) remains an incurable hematologic malignancy despite significant advances in treatment in recent years. A deeper understanding of the disease biology—including the bone marrow microenvironment, mechanisms of disease progression, and treatment resistance—is essential for the development of future therapies. This Special Issue invites a broad range of contributions that reflect the diverse and evolving landscape of MM research. We welcome studies across all stages of research, including basic, translational, and clinical investigations in areas such as molecular biology, immunology, novel therapeutic strategies, clinical trials, and real-world data. In particular, we strongly encourage submissions focusing on immunology and immunotherapeutic approaches, including monoclonal antibodies, CAR-T cells, bispecific antibodies, and antibody-drug conjugates, which are playing an increasingly central role in MM treatment. Submissions may include original research articles, comprehensive reviews, and expert perspectives. Through this Special Issue, we aim to foster a deeper understanding of MM and contribute to future advances in treatment and patient care by assembling an inclusive body of knowledge.
Dr. Ichiro Hanamura
Guest Editor
Manuscript Submission Information
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Keywords
- multiple myeloma
- bone marrow microenvironment
- disease biology
- disease progression
- treatment resistance
- CAR-T cells
- bispecific antibodies (BsAbs)
- antibody-drug conjugates (ADCs)
- tumor–host interaction
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