Integrative Approaches to Musculoskeletal Disorders Using Natural Products
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 3
Special Issue Editor
Interests: natural products; osteoporosis; osteoclast; bone-related diseases; bone
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
With the global population aging rapidly, the demand for maintaining musculoskeletal health in later life has never been greater. Aging is closely associated with metabolic dysfunctions that contribute to disorders such as osteoporosis, sarcopenia, and obesity—all of which severely impact the quality of life in older adults. However, current pharmacological treatments are often hindered by high costs or severe side effects, limiting long-term adherence in patients.
Natural products and their derivatives have emerged as promising alternatives due to their multi-target potential, safety, and historical usage. Moreover, these musculoskeletal disorders are often interconnected, with one condition aggravating another—highlighting the need for integrated therapeutic strategies. This Special Issue will explore the role of natural compounds, herbal extracts, and low-molecular-weight phytochemicals in modulating musculoskeletal health.
We invite original research and reviews on natural products that target individual or combined conditions, such as osteoporosis, sarcopenia, or osteosarcopenic obesity syndrome. Studies focusing on bone–muscle crosstalk, mechanistic insights, and novel herbal combinations are particularly welcome.
Dr. Jae-Hyun Kim
Guest Editor
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Keywords
- natural products
- bone metabolism
- sarcopenia
- osteoporosis
- herbal medicine
- osteo-sarcopenic obesity
- bone–muscle crosstalk
- low-molecular-weight compounds
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