Genetic Testing and Tailored Treatment for Thyroid Disorders: Molecular Basis and New Trends
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: closed (20 November 2025) | Viewed by 1336
Special Issue Editor
Interests: minimal invasive and robotic surgery in breast and endocrine disease; precision medicine and genomic research in surgical oncology
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Special Issue Information
Dear Colleagues,
Thyroid diseases are a group of common endocrine disorders with diverse clinical presentations and significant health consequences. Recent advances in genetic research have unveiled the complex genetic architecture of thyroid diseases, offering new insights into disease pathogenesis and opening new avenues for personalized medicine. This Special Issue focuses on the latest developments in the genetic basis and emerging therapeutic approaches for thyroid diseases.
Key topics:
- Genetic epidemiology: in-depth analysis of genetic variants and risk factors associated with various thyroid diseases, including thyroid cancer, Graves’ disease, hypothyroidism, and Hashimoto’s thyroiditis;
- Functional genomics: elucidation of the molecular mechanisms underlying thyroid disease-associated genetic variants, including their impact on gene expression, protein function, and cellular signaling pathways;
- Personalized medicine: development and implementation of individualized treatment strategies based on genetic information, including targeted therapies, gene therapy, and precision medicine;
- Novel therapeutic targets: identification and validation of novel therapeutic targets for thyroid diseases, with a focus on druggable genes and pathways.
This Special Issue seeks to offer a thorough understanding of the current state of knowledge in the field of thyroid disease genetics and encourage additional research in this rapidly advancing field. The effective integration of genetic knowledge with clinical practice has the potential to enhance the diagnosis, prognosis, and treatment of thyroid disorders, thereby resulting in improved patient outcomes. Since IJMS is a journal of molecular science, pure clinical studies or sociological research will not be suitable for our journal. However, clinical submissions with biomolecular experiments are welcomed.
Dr. Kyoung Sik Park
Guest Editor
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Keywords
- thyroid diseases
- genetics
- personalized medicine
- novel therapies
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