Current Advances in Immuno-Oncology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 September 2026 | Viewed by 1844
Special Issue Editor
Special Issue Information
Dear Colleagues,
Immuno-oncology has emerged as one of the most transformative fields in cancer research and therapy, reshaping our understanding of tumor biology and the host immune response. The development of immune checkpoint inhibitors, cancer vaccines, adoptive cell therapies, and innovative biomarker-driven approaches has provided new opportunities to improve survival and quality of life for patients with various malignancies. Nevertheless, major challenges remain, including the mechanisms of resistance, variability of patient response, identification of predictive biomarkers, and management of immune-related adverse effects.
This Special Issue of the International Journal of Molecular Sciences, “Current Advances in Immuno-Oncology”, aims to highlight cutting-edge advances in the molecular and cellular mechanisms underlying tumor–immune interactions as well as translational and clinical insights into novel immunotherapeutic strategies.
We welcome original research articles, short communications, and comprehensive reviews. Topics of interest include, but are not limited to, the following topics:
- Molecular mechanisms of tumor–immune evasion;
- Tumor microenvironment and immunometabolism;
- Checkpoint inhibitors: novel targets and resistance mechanisms;
- CAR-T cells, NK cell therapies, and other engineered immune approaches;
- Cancer vaccines and oncolytic viruses;
- Microbiome–immune system interactions in cancer therapy;
- Biomarkers for patient stratification and therapy monitoring;
- Combination therapies integrating immunotherapy with chemotherapy, radiotherapy, or targeted agents;
- Systems biology, AI, and computational models in immuno-oncology research.
By bringing together contributions from basic, translational, and clinical perspectives, this Special Issue will provide a comprehensive overview of recent advances in immuno-oncology and outline directions for future research and therapeutic applications.
We look forward to your valuable contributions to this Special Issue.
Dr. Gratiela Grădișteanu Pircălabioru
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- immuno-oncology
- tumor microenvironment
- immune checkpoint inhibitors
- CAR-T cells
- adoptive cell therapy
- cancer vaccines
- oncolytic viruses
- tumor immune evasion
- immunometabolism
- biomarkers
- tumor immunology
- microbiome and cancer
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
