Current Advances in Immuno-Oncology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 March 2026 | Viewed by 30
Special Issue Editor
Special Issue Information
Dear Colleagues,
Immuno-oncology has emerged as one of the most transformative fields in cancer research and therapy, reshaping our understanding of tumor biology and the host immune response. The development of immune checkpoint inhibitors, cancer vaccines, adoptive cell therapies, and innovative biomarker-driven approaches has provided new opportunities to improve survival and quality of life for patients with various malignancies. Nevertheless, major challenges remain, including the mechanisms of resistance, variability of patient response, identification of predictive biomarkers, and management of immune-related adverse effects.
This Special Issue of the International Journal of Molecular Sciences, “Current Advances in Immuno-Oncology”, aims to highlight cutting-edge advances in the molecular and cellular mechanisms underlying tumor–immune interactions as well as translational and clinical insights into novel immunotherapeutic strategies.
We welcome original research articles, short communications, and comprehensive reviews. Topics of interest include, but are not limited to, the following topics:
- Molecular mechanisms of tumor–immune evasion;
- Tumor microenvironment and immunometabolism;
- Checkpoint inhibitors: novel targets and resistance mechanisms;
- CAR-T cells, NK cell therapies, and other engineered immune approaches;
- Cancer vaccines and oncolytic viruses;
- Microbiome–immune system interactions in cancer therapy;
- Biomarkers for patient stratification and therapy monitoring;
- Combination therapies integrating immunotherapy with chemotherapy, radiotherapy, or targeted agents;
- Systems biology, AI, and computational models in immuno-oncology research.
By bringing together contributions from basic, translational, and clinical perspectives, this Special Issue will provide a comprehensive overview of recent advances in immuno-oncology and outline directions for future research and therapeutic applications.
We look forward to your valuable contributions to this Special Issue.
Dr. Gratiela Grădișteanu Pircălabioru
Guest Editor
Manuscript Submission Information
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Keywords
- immuno-oncology
- tumor microenvironment
- immune checkpoint inhibitors
- CAR-T cells
- adoptive cell therapy
- cancer vaccines
- oncolytic viruses
- tumor immune evasion
- immunometabolism
- biomarkers
- tumor immunology
- microbiome and cancer
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