Molecular Mechanism of Hypertension-Induced Renal Injury
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 163
Special Issue Editors
Interests: hypertension; renal injury; pharmacology; chemonephrotoxicity; molecular mechanisms of chronic kidney failure
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hypertension-induced renal injury represents a significant public health challenge worldwide, contributing to the development of chronic kidney disease and end-stage renal failure. Despite advances in the management of hypertension, its damaging effects on renal tissue often persist, creating an urgent need for novel therapeutic approaches and molecular insights into the pathogenesis of kidney injury. Understanding the molecular mechanisms underlying this injury is essential for developing effective strategies to mitigate the damaging effects of hypertension on kidneys. This Special Issue, entitled “Molecular Mechanism of Hypertension-Induced Renal Injury”, aims to highlight recent advances in the field.
This Special Issue welcomes research on the cellular and molecular pathways associated with hypertensive damage, including pathways of hypertensive renal damage, protective factors, and potential therapeutic targets. We particularly welcome the submission of studies that explore innovative treatment strategies and novel pharmacological interventions to prevent or mitigate renal injury due to hypertension. We also welcome submissions addressing the genetic and epigenetic changes that predispose individuals to hypertensive renal disease, as well as the impact of immune cell activation on renal health. In addition, we seek studies that present the outcomes of employing unconventional methods in the management of obesity and hypertension, including dietary strategies such intermittent fasting, ketogenic diets and the DASH diet, as well as bariatric surgery. By compiling innovative research in these areas, this Special Issue aims to advance our understanding of hypertension-related renal injury and inform future therapeutic strategies.
We welcome original research articles, reviews, and case studies that offer insights into molecular and cellular mechanisms.
Prof. Dr. Ningjun Li
Dr. Guangbi Li
Guest Editors
Manuscript Submission Information
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Keywords
- hypertension
- renal injury
- molecular mechanisms
- chronic kidney disease
- pharmacological interventions
- vascular biology
- renoprotection
- blood pressure regulation
- toxicology
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