Molecular Study on Biofunctional Properties of Plant Bioactives

Dear Colleagues,

Plant extracts represent an extraordinary source of structurally diverse bioactive molecules capable of modulating key biochemical and molecular pathways relevant to human health. With the rapid expansion of omics technologies, high-resolution analytical methods, and advanced in vitro and in vivo models, we are now able to explore these natural compounds with unprecedented depth and precision. Nevertheless, the molecular mechanisms that underlie their antioxidant, anti-inflammatory, metabolic, cardioprotective, neuroprotective, and immunomodulatory activities remain only partially understood.

This Special Issue, “Molecular Study on Biofunctional of Plant Bioactives”, aims to bring together cutting-edge research that clarifies the molecular targets, signaling pathways, receptor interactions, and structure–activity relationships of plant-derived compounds. We particularly encourage studies employing molecular docking, transcriptomics, proteomics, metabolomics, cellular models, and animal systems to dissect functional effects at the mechanistic level.

By gathering high-quality original research and comprehensive reviews, this Special Issue seeks to advance our understanding of plant bioactives and inspire the development of innovative, evidence-based natural therapeutics.

We warmly welcome your contributions.

Dr. Isidora Milosavljevic
Dr. Jovana N. Novakovic
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.