Sleep and Breathing: From Molecular Perspectives
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 December 2025 | Viewed by 502
Special Issue Editor
2. Facultad de Medicina, Universidad de las Islas Baleares, 07122 Palma, Spain
Interests: sleep and breathing
Special Issue Information
Dear Colleagues,
Obstructive sleep apnea (OSA) is a prevalent and complex disease that increases the risk of relevant clinical consequences such as cardiovascular, metabolic, and cerebrovascular diseases. Improving our understanding of what causes the complexity and diversity of OSA is a major challenge for researchers.
This Special Issue will contribute to our understanding of the molecular mechanisms of OSA and its consequences, as well as the applicability of different biomarkers for both the diagnosis of OSA and identification of those patients at risk of OSA-related complications. Additionally, studies on the molecular mechanisms of chronic intermittent hypoxia and sleep fragmentation that occur during sleep with regard to the main signaling pathways (including gut microbiota disbiosis, oxidative stress, systemic inflammation, and sympathetic activation) and epigenetics alterations, such as microRNA, long non-coding RNA, and DNA methylation, are welcome. Original studies, as well as review articles, are welcome in this Special Issue, where cutting-edge methodologies might also be considered. The spread of such advances will provide the basis and standards for further research and the development of new diagnostic and therapeutic approaches.
Dr. Alberto Alonso-Fernández
Guest Editor
Manuscript Submission Information
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Keywords
- obstructive sleep apnea
- cardiovascular risk
- cardiovascular diseases/physiopathology
- continuous positive airway pressure
- hypertension
- biomarkers
- diabetes
- pregnancy
- gene expression profiling
- genetic markers
- inflammation mediators
- oxidative stress
- proteomics
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