Treatment of Neurodegenerative Diseases with Natural Products
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 602
Special Issue Editor
Interests: neurodegenerative diseases; metabolomics; drug-drug interaction; gut-brain axis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurodegenerative diseases are diseases whose prevalence is increasing due to the aging of society. Various genetic and environmental risk factors of neurodegenerative diseases exist, and they interact sophisticatedly. Since the mechanisms involved in the pathologies of neurodegenerative diseases are complicated, recently, the use of natural products for treating neurodegenerative diseases has been attracting attention. Natural products consist of extracts, fractions, or active compounds of one or more plants. Uncovering the mechanism of action of a natural product with multiple functions against neurodegenerative diseases can provide new clues for the treatment. Among the mechanisms involved in these pathologies, it is important to determine whether natural products can thwart such mechanisms as inflammation, oxidative stress, cell death, and misfolding protein accumulation. In particular, research on microbiota–gut–brain axis-mediated mechanisms of action of natural products on neurodegenerative diseases is also welcome, which has recently been attracting attention.
This Special Issue will consider papers presenting effects and mechanisms of action of natural products for various neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, amyothrophic lateral sclerosis, and multiple sclerosis. In addition to in vivo, in vitro, and in silico studies, articles utilizing clinical evidence (systematic reviews or meta-analysis) are welcome.
Dr. Eugene Huh
Guest Editor
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Keywords
- neurodegenerative diseases
- natural product
- misfolding protein aggregation
- oxidative stress
- neuroinflammation
- autophagy
- apoptosis
- microbiota–gut–brain axis
- therapeutic
- prevention
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