Cyclic and Heterocyclic Compounds in Drug Synthesis and Delivery
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 6505
Special Issue Editor
Special Issue Information
Dear Colleagues,
Currently, medicinal chemistry has become one of the main areas of chemistry. The search for biological activity is carried out even with compounds that were previously difficult to imagine as medicinal. Heterocyclic compounds are a huge component of medicinal chemistry and exhibit the widest range of biological activity. More and more attention is being given by researchers to these natural compounds or their analogues. Cyclic, polycyclic and cage compounds such as camphor, fenchon and adamantane have become common structural elements of potential drugs.
In recent years, in vitro testing has become incredibly accessible, and the availability of in vivo testing has increased dramatically. Thousands of compounds have been tested and thousands are being tested right now. In this regard, the attention of researchers began to switch to improving the pharmacokinetic properties of their molecules. The number of publications devoted to drug delivery is growing rapidly. Additionally, it is most likely that in the coming years, the focus of researchers will slightly shift from the synthesis of new molecules to the improvement of already known ones and the development of methods for their delivery. This Special Issue will feature papers on the synthesis of new biologically active compounds based on cyclic, heterocyclic and cage building blocks, studies on the modification of such compounds in order to increase their water solubility and other pharmacokinetic properties, and the development of delivery methods for such compounds.
Suggested topics include, but are not limited to:
- Methods for the synthesis of cyclic, heterocyclic and cage organic molecules;
- Studies of biological activity;
- Modification of molecules to increase druglikeness;
- Development of drug delivery methods;
- Study of metabolism and pharmacokinetics.
Dr. Vladimir V. Burmistrov
Guest Editor
Manuscript Submission Information
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Keywords
- heterocycles
- cyclic compounds
- cage compounds
- terpenes
- drug discovery
- drug delivery
- biological activity
- drug metabolism
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