Molecular Synapse: Diversity, Function and Signaling
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 18
Special Issue Editor
Special Issue Information
Dear Colleagues,
Synaptic signaling is the process by which neurons communicate at synapses, transmitting signals via chemical messengers called neurotransmitters. It underpins information processing in the brain and is governed by complex molecular dynamics that control the speed, precision and, critically, plasticity of neuronal communication. This involves the ultrafast choreography of presynaptic proteins to release neurotransmitters, as well as the rapid, regulated movement of receptors and scaffolds in the postsynaptic membrane. More recently, it has become clear that synapses are highly diverse in their protein composition, both across and within cell types. New approaches are needed to visualize, dissect and understand the complex machinery of synaptic signaling. This Special Issue will be of interest to basic and clinical researchers studying the molecular and dynamic aspects of synaptic signaling and its disruptions under disease conditions, including theoretical (computational modeling) applications.
Dr. Oksana Sorokina
Guest Editor
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Keywords
- synaptic signaling
- synaptic plasticity
- brain disorders
- synapse diversity
- molecular composition of synapse
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