ijms-logo

Journal Browser

Journal Browser

Natural Product-Based Strategy for Skin Inflammatory Disorders and Regeneration

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 20 March 2025 | Viewed by 1349

Special Issue Editor


E-Mail Website
Guest Editor
Department of Medical Science, College of Medical Sciences, Soonchunhyang University, Asan 31538, Republic of Korea
Interests: exosome; inflammation; natural extract
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is supervised by Prof. Dr. Mi Young Lee with the assistance of our Topical Advisory Panel Member Dr. Ji-Hye Kang (Soonchunhyang University).

There has been an emerging interest in natural products and medicinal plants for inflammatory skin disorders and regeneration.

Bioactive natural products and medicinal plants have been known to exert pro-health effects on the skin via anti-oxidative, collagen biosynthesis-promoting, immunomodulatory, wound healing and anti-inflammatory activities, among other benefits.

Therefore, in this Special Issue, we closely consider the current knowledge and applications of bioactive natural compounds and their derivatives and conjugates, as well as plant extracts in the pharmaceutical and cosmetic fields.

The following subtopics may be covered:

  • Biological activities and applications of bioactive natural compounds and their derivatives and conjugates for the treatment of skin inflammation, wound healing and regeneration and aging in the pharmaceutical and cosmetic industries;
  • The beneficial effects of medicinal plant extracts on skin inflammation, wound healing and regeneration and aging in the pharmaceutical and cosmetic industries;
  • Molecular mechanism underlying the pro-health effects on skin inflammation and the related disorders, including atopic dermatitis, psoriasis acne, etc.;
  • Molecular mechanisms underlying the pro-health effects on wound healing, regeneration and aging.

Prof. Dr. Mi Young Lee
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • inflammatory skin disorders
  • skin wound healing and regeneration
  • skin aging
  • bioactive natural compound
  • derivative and conjugate
  • plant extract
  • beneficial effect and application
  • molecular mechanism

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

13 pages, 2615 KiB  
Article
Evaluating the Dermatological Benefits of Snowberry (Symphoricarpos albus): A Comparative Analysis of Extracts and Fermented Products from Different Plant Parts
by Chanwoo Lee, Hana Cho, Myunsoo Kim, Boae Kim, Young-Pyo Jang and Junseong Park
Int. J. Mol. Sci. 2024, 25(17), 9660; https://doi.org/10.3390/ijms25179660 - 6 Sep 2024
Viewed by 840
Abstract
Skin ageing is influenced by both intrinsic and extrinsic factors, with excessive ultraviolet (UV) exposure being a significant contributor. Such exposure can lead to moisture loss, sagging, increased wrinkling, and decreased skin elasticity. Prolonged UV exposure negatively impacts the extracellular matrix by reducing [...] Read more.
Skin ageing is influenced by both intrinsic and extrinsic factors, with excessive ultraviolet (UV) exposure being a significant contributor. Such exposure can lead to moisture loss, sagging, increased wrinkling, and decreased skin elasticity. Prolonged UV exposure negatively impacts the extracellular matrix by reducing collagen, hyaluronic acid, and aquaporin 3 (AQP-3) levels. Fermentation, which involves microorganisms, can produce and transform beneficial substances for human health. Natural product fermentation using lactic acid bacteria have demonstrated antioxidant, anti-inflammatory, antibacterial, whitening, and anti-wrinkle properties. Snowberry, traditionally used as an antiemetic, purgative, and anti-inflammatory agent, is now also used as an immune stimulant and for treating digestive disorders and colds. However, research on the skin benefits of Fermented Snowberry Extracts remains limited. Thus, we aimed to evaluate the skin benefits of snowberry by investigating its moisturising and anti-wrinkle effects, comparing extracts from different parts of the snowberry plant with those subjected to fermentation using Lactobacillus plantarum. Chlorophyll-free extracts were prepared from various parts of the snowberry plant, and ferments were created using Lactobacillus plantarum. The extracts and ferments were analysed using high-performance liquid chromatography (HPLC) to determine and compare their chemical compositions. Moisturising and anti-ageing tests were conducted to assess the efficacy of the extracts and ferments on the skin. The gallic acid content remained unchanged across all parts of the snowberry before and after fermentation. However, Fermented Snowberry Leaf Extracts exhibited a slight decrease in chlorogenic acid content but a significant increase in ferulic acid content. The Fermented Snowberry Fruit Extract demonstrated increased chlorogenic acid and a notable rise in ferulic acid compared to its non-fermented counterpart. Skin efficacy tests revealed that Fermented Snowberry Leaf and Fruit Extracts enhanced the expression of AQP-3, HAS-3, and COL1A1. These extracts exhibited distinct phenolic component profiles, indicating potential skin benefits such as improved moisture retention and protection against ageing. These findings suggest that Fermented Snowberry Extracts could be developed into effective skincare products, providing a natural alternative for enhancing skin hydration and reducing signs of ageing. Full article
Show Figures

Figure 1

Back to TopTop