Molecular Determinants of Neuromotor Control, Tremor, and Fatigue
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 July 2026 | Viewed by 1616
Special Issue Editor
Interests: neuromuscular physiology; neuromotor control; physiological tremor; muscle fatigue; sensorimotor integration; biomechanics; molecular mechanisms of muscle function; excitation–contraction coupling; fatigue biomarkers; neuromuscular adaptation
Special Issue Information
Dear Colleagues,
Neuromotor control, physiological tremor, and muscle fatigue arise from complex interactions between molecular, neurophysiological, and biomechanical mechanisms. Oscillatory muscle activity, motor unit behavior, ion-channel dynamics, metabolic regulation, and sensorimotor feedback contribute to both normal neuromuscular function and dysfunction across clinical, athletic, and aging populations. Recent advances in molecular physiology and high-resolution biosignal analysis provide new opportunities to link molecular-level processes with measurable functional outcomes such as tremor variability, neuromuscular response to physical effort, and adaptation to targeted interventions.
This Special Issue aims to explore the molecular mechanisms, pathways, and biomarkers underlying neuromotor control, tremor generation, fatigue development, and neuromuscular adaptation. We welcome studies integrating molecular biology, neurophysiology, biomechanics, applied human research, and computational approaches. Topics include, but are not limited to, ion-channel physiology, excitation–contraction coupling, neuromuscular transmission, molecular determinants of muscle fatigue, biomarkers of neuromuscular performance, and sensorimotor regulation.
In this Special Issue, original research articles and comprehensive reviews are welcome. Research areas may include, but are not limited to, the following:
- Molecular pathways regulating neuromuscular control and motor unit activity;
- Ion-channel dynamics and excitation–contraction coupling;
- Molecular and cellular determinants of muscle fatigue and recovery;
- Biomarkers of neuromuscular performance and stress;
- Mechanisms of physiological tremor and oscillatory muscle activity;
- Sensorimotor integration at molecular and neurophysiological levels;
- Effects of physical effort, temperature modulation, or neuromuscular stimulation;
- Molecular dysregulation in neuromuscular disorders.
We look forward to receiving your contributions.
Dr. Szymon Kulis
Guest Editor
Manuscript Submission Information
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Keywords
- neuromuscular control
- physiological tremor
- muscle fatigue
- sensorimotor integration
- motor unit physiology
- muscle oscillations
- neuromuscular adaptation
- excitation–contraction coupling
- fatigue biomarkers
- neurophysiology of movement
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