Molecular Determinants of Neuromotor Control, Tremor, and Fatigue
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 July 2026 | Viewed by 39
Special Issue Editor
Interests: neuromuscular physiology; neuromotor control; physiological tremor; muscle fatigue; sensorimotor integration; biomechanics; molecular mechanisms of muscle function; excitation–contraction coupling; fatigue biomarkers; neuromuscular adaptation
Special Issue Information
Dear Colleagues,
Neuromotor control, physiological tremor, and muscle fatigue arise from complex interactions between molecular, neurophysiological, and biomechanical mechanisms. Oscillatory muscle activity, motor unit behavior, ion-channel dynamics, metabolic regulation, and sensorimotor feedback contribute to both normal neuromuscular function and dysfunction across clinical, athletic, and aging populations. Recent advances in molecular physiology and high-resolution biosignal analysis provide new opportunities to link molecular-level processes with measurable functional outcomes such as tremor variability, neuromuscular response to physical effort, and adaptation to targeted interventions.
This Special Issue aims to explore the molecular mechanisms, pathways, and biomarkers underlying neuromotor control, tremor generation, fatigue development, and neuromuscular adaptation. We welcome studies integrating molecular biology, neurophysiology, biomechanics, applied human research, and computational approaches. Topics include, but are not limited to, ion-channel physiology, excitation–contraction coupling, neuromuscular transmission, molecular determinants of muscle fatigue, biomarkers of neuromuscular performance, and sensorimotor regulation.
In this Special Issue, original research articles and comprehensive reviews are welcome. Research areas may include, but are not limited to, the following:
- Molecular pathways regulating neuromuscular control and motor unit activity;
- Ion-channel dynamics and excitation–contraction coupling;
- Molecular and cellular determinants of muscle fatigue and recovery;
- Biomarkers of neuromuscular performance and stress;
- Mechanisms of physiological tremor and oscillatory muscle activity;
- Sensorimotor integration at molecular and neurophysiological levels;
- Effects of physical effort, temperature modulation, or neuromuscular stimulation;
- Molecular dysregulation in neuromuscular disorders.
We look forward to receiving your contributions.
Dr. Szymon Kulis
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neuromuscular control
- physiological tremor
- muscle fatigue
- sensorimotor integration
- motor unit physiology
- muscle oscillations
- neuromuscular adaptation
- excitation–contraction coupling
- fatigue biomarkers
- neurophysiology of movement
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
