Advances in Photodynamic Therapy and Photodetection: Targeted Approaches and Immunological Perspectives
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 134
Special Issue Editor
Special Issue Information
Dear Colleagues,
Photodynamic therapy (PDT) is a treatment modality that involves the administration of a photosensitizer (PS) which, after exposure to light of a specific wavelength, leads to photochemical and photobiological reactions that, in the presence of oxygen, result in the generation of singlet oxygen and subsequent cell and tissue damage. Since the first discovery of the potential of PDT for the treatment of oncological diseases, many different malignant and non-malignant therapies have been developed.
Photodetection (PD) is a broad term for optical techniques that detect light from tissue and rely on different photophysical phenomena, including fluorescence, reflectance, absorption, and scattering. One example of PD is fluorescence-guided surgery (FGS), which aims to demarcate a lesion from the surrounding healthy tissues.
Targeted PDT and nanotechnology have recently contributed to the further development of PDT and PD. Immunological reactions to PDT, as well as the potential for combining PDT with immunotherapy, have gained increasing interest in recent years.
This Special Issue aims to provide an update on the current status of PDT and PD, with an emphasis on targeted approaches and immunological involvement.
Dr. Henriëtte S. De Bruijn
Guest Editor
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Keywords
- photodynamic therapy (PDT)
- photodetection (PD)
- photosensitiser
- nanoparticles
- nanotechnology
- targeted therapy
- immunotherapy
- vaccines
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