Microbial Biofilms in Health and Disease: Molecular Perspectives
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 30 March 2026 | Viewed by 7
Special Issue Editor
Interests: Helicobacter pylori; biofilm; coccoid forms; morphology; outer membrane vesicles; antibiotic tolerance; antimicrobial/antibiofilm activity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Biofilm is a highly complex structure composed of microorganisms embedded in a thick extracellular matrix. The close proximity of microbial cells and the presence of this matrix give rise to unique characteristics, including an increased rate of gene acquisition and reduced susceptibility to antimicrobials and the immune system. These features enable biofilm populations to colonize niches inaccessible to their planktonic counterparts.
Over the last decade, biofilm research has undergone major advances, from redefining the stages of biofilm formation to identifying free-floating biofilm forms and recognizing biofilm as an entity encased by multiple structures and biomacromolecules (the so-called matrixome).
To further advance research in this area, this Special Issue invites scientists and clinicians to submit original research articles, short communications, and reviews describing molecular processes underlying biofilm development and the impact of biofilms on human and animal health and disease. Submissions focusing on the role of specific genes in biofilm development, omics-based analyses (transcriptomics, proteomics, and metabolomics), and in silico approaches to identify new anti-biofilm compounds are particularly encouraged.
Dr. Paweł Krzyżek
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biofilm
- antibiofilm
- biofilm matrix
- matrixome
- antibiotic resistance
- antibiotic tolerance
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