Emerging Roles of Extracellular Vesicles in Neurological Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 25 July 2026 | Viewed by 269
Special Issue Editor
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs), including exosomes and microvesicles, have emerged as central mediators of intercellular communication within the central and peripheral nervous systems. EVs carry a diverse molecular cargo composed of proteins, lipids, metabolites, and nucleic acids, including mRNA, microRNA, long non-coding RNA, circular RNA, and DNA fragments, enabling precise cell-specific signaling in both health and disease. Increasing evidence implicates EVs in the pathogenesis, progression, and recovery of a wide range of neurological disorders, including neurodegenerative diseases, brain tumors, stroke, traumatic brain injury, neuroinflammatory conditions, and neuromuscular diseases. This Special Issue aims to highlight recent advances in our understanding of the emerging roles of extracellular vesicles in neurological diseases. Topics of interest include fundamental insights into EV biogenesis, cargo selection, and cell-specific communication, as well as EV-mediated neuroimmune signaling, neurovascular interactions, and neuron–glia communication. The issue also encompasses translational applications such as EV-based biomarkers, liquid biopsy approaches using cerebrospinal fluid, blood, and other biofluids, and the development of EVs as therapeutic delivery platforms.
Dr. Anudeep Yekula
Guest Editor
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Keywords
- extracellular vesicles
- exosomes
- neurological diseases
- liquid biopsy
- neurodegeneration
- neuro-oncology
- biomarkers
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