Molecular Linkage Between Trace Elements and Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (20 June 2025) | Viewed by 535
Special Issue Editor
Interests: neuro-oncology; molecular biology; pathology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Zinc, copper, and selenium play essential roles in brain health; their specific impact on glioma development remains an area of ongoing investigation. The purpose of understanding these trace elements’ complicated interactions may provide valuable insights for future therapeutic approaches. Zinc is an essential trace element with antioxidant properties. It plays a crucial role in maintaining a healthy central nervous system and is involved in DNA replication, protein synthesis, and metabolism. Some studies have suggested a protective effect of dietary zinc against brain tumor development. However, overall evidence remains inconclusive, and a significant association has been observed between zinc intake and tumor growth in cancer. Copper is another essential trace element. It functions as a cofactor for various enzymes and proteins. Recent research has explored the potential anticancer activity of copper nanoparticles. These nanoparticles target mitochondria, modulate oxidative stress, induce apoptosis, and impact immune responses. Selenium is vital for human health and is incorporated into selenoproteins. It acts as an antioxidant and supports immune function. Some studies have investigated the relationship between selenium levels and cancer.
This Special Issue will summarize the current state of unraveling molecular insights into how trace element dysregulation may contribute to cancer progression.
Dr. Daizo Yoshida
Guest Editor
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Keywords
- cancer
- cell signaling
- chelation
- copper
- selenium
- trace element
- zinc
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