Mechanisms and Effects of Toxic Chemical Elements and Their Harmful Compounds on Metabolism, Endocrine and Nervous Systems of Humans
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Toxicology and Public Health".
Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 6017
Special Issue Editors
Interests: bioanalytics; pathobiochemistry; environmental and food chemistry; diets; trace elements; heavy metals; toxicity; selenium and iodine in autism; spectrum disorders; obesity; thyroid pathologies; clinical samples; medical applications of modern instrumental techniques; validation studies
Special Issues, Collections and Topics in MDPI journals
Interests: diabetes mellitus; obesity; polycystic ovarian syndrome;, thyroid disorders; thyroid cancer; hyperthyroidism; hypothyroidism; parathyroid and calcium disorders; pituitary disorders; health effects of toxic chemical elements
Interests: fatty liver disease; liver diseases; cholecystectomy; micronutrients; macronutrients
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Homeostasis, a complex process of the regulation of all the functions in the human body, maintains the internal bodily environment. However, any level of deviation from the normal structural state (i.e., chemical imbalance) may (and often does) result in the development of the disease. Therefore, scientists from a wide variety of research fields determine bodily deficiencies of chemical elements, their toxicity, and exposure potential, which are accountable for the development of specific diseases in humans. Scientific reports concerning this matter do not often give the big picture of the mechanisms and causes responsible for the occurrence or exacerbation of a certain disease’s symptoms and signs.
Research into the content and function of various toxic and potentially toxic chemical elements and their compounds has long been conducted, and along with the technological development it has been able to provide extensive knowledge in this field. Yet, since the observation of the changing elemental content, distribution, bioavailability, and interactions between the essential/nonessential and toxic elements in the human body is not an easy task, current knowledge, though extensive, is still insufficient to explain the etiology of certain diseases. What is more, the self-regulation mechanisms in disease may be disturbed by diet, stress, lifestyle factors, and the body’s specific susceptibility to a certain disease. Therefore, single and multi-elemental or multi-compound analyses should be interpreted in a broader and more complex context.
This Special Issue aims to present research articles as well as critical reviews that address challenges to see and understand the role of specific toxic and potentially toxic chemical elements and their harmful compounds in the development of diseases in humans. Hopefully, this will shed more light on various roles that chemical elements play in humans, and help us to better understand the human body’s susceptibility to certain disorders, especially those of the metabolic nature of the endocrine and nervous systems.
Best regards,
Dr. Anna Błażewicz
Dr. Katarzyna Ewa Skórzyńska-Dziduszko
Dr. Jacek Baj
Guest Editors
Manuscript Submission Information
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Keywords
- toxic elements
- toxic compounds
- toxic effects on metabolism
- nervous system
- endocrine system
- health risk assessment
- chemical interactions in the human body
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