Advances in Shrimp Physiology and Genomics

A special issue of Fishes (ISSN 2410-3888). This special issue belongs to the section "Aquatic Invertebrates".

Deadline for manuscript submissions: 15 April 2026 | Viewed by 271

Special Issue Editors


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Guest Editor
School of Marine Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China
Interests: crustaceans; genetics and genome; molecular biology; aquatic physiology

E-Mail Website
Guest Editor
School of Marine Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China
Interests: aquaculture; crustaceans; environmental stress; ecology

Special Issue Information

Dear Colleagues,

Shrimp represent one of the most economically significant and widely farmed groups in global aquaculture, being of growing importance to food security. Recent advances in physiological and genomic research have greatly enhanced our understanding of shrimp biology, although many mechanisms remain unexplored. This Special Issue, “Advances in Shrimp Physiology and Genomics”, aims to gather high-quality research addressing the molecular, functional, and applied aspects of shrimp biology. We welcome contributions that utilize genomic, transcriptomic, proteomic, and metabolomic approaches that elucidate the fundamental physiological processes in shrimp. Key topics of interest include, but are not limited to, the following:

​Molecular Physiology:​​ Investigating the mechanisms  underlying growth, reproduction, metabolism, neuroendocrinology, and osmoregulation.

​Stress and Adaptation:​​ Exploring genomic and physiological responses to biotic (e.g., pathogens) and abiotic (e.g., temperature, salinity, pollution) stressors.

​Immunogenomics:​​ Analyzing  the shrimp immune system through genomic lenses, including pathogen–host interactions and vaccine development.

​Functional Genomics:​​ Utilizing CRISPR/Cas9, RNAi, and other tools to validate gene function and trait mechanisms.

​Applied Genomics:​​ Genomic selection, marker-assisted breeding, and the development of genetic tools for improving aquaculture traits such as disease resistance and growth rate.​

We look forward to receiving your contributions.

Dr. Zhongkai Wang
Prof. Dr. Yuquan Li
Guest Editors

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Keywords

  • crustaceans
  • shrimp
  • aquaculture
  • physiology
  • genomics
  • genetics
  • transcriptomics
  • proteomics
  • metabolomics

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Published Papers (1 paper)

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Research

17 pages, 3523 KB  
Article
Silencing of the Superaquaporin LvAQP11 Disrupts Salinity Tolerance, Molting Cycle, and Myofibril Organization in Litopenaeus vannamei
by Zhongkai Wang, Guanghao Song, Shikui Zhang, Long Zhang, Beibei Wang, Kunpeng Zhao, Yanting Cui, Fei Liu, Renjie Wang and Yuquan Li
Fishes 2025, 10(12), 631; https://doi.org/10.3390/fishes10120631 - 9 Dec 2025
Viewed by 130
Abstract
The Pacific white shrimp (Litopenaeus vannamei), a euryhaline crustacean of significant economic importance, is widely cultivated for its adaptability to diverse salinity levels. Aquaporins (AQPs) are membrane channel proteins that mediate the transport of water and small solutes across biological membranes. [...] Read more.
The Pacific white shrimp (Litopenaeus vannamei), a euryhaline crustacean of significant economic importance, is widely cultivated for its adaptability to diverse salinity levels. Aquaporins (AQPs) are membrane channel proteins that mediate the transport of water and small solutes across biological membranes. Among them, aquaporin 11 (AQP11) is classified as a superaquaporin, and its physiological roles remain unclear. In this study, RNA interference (RNAi) was employed to silence AQP11 expression in L. vannamei, followed by RNA-seq analysis to investigate transcriptomic responses. Differentially expressed genes (DEGs) were identified by comparing dsAQP11 and control groups. The LvAQP11 knockdown significantly increased mortality to 76.7% under acute high-salinity stress (50‰) but not under low-salinity conditions (10‰). Transcriptomic analysis revealed that LvAQP11 deficiency disrupted amino acid metabolism pathways and triggered endoplasmic reticulum stress, as evidenced by the upregulation of proteasome subunits and unfolded protein response genes. Furthermore, silencing LvAQP11 delayed molting progression in the premolt stages, accompanied by the significant upregulation of molt-inhibiting hormone (LvMIH1/5) and downregulation of retinoic acid X receptor (LvRXR). The long-term silencing of LvAQP11 did not affect the weight gain rate (WGR) or the specific growth rate (SGR) but induced muscle fiber disorganization and significantly increased muscle water content. RNA sequencing identified enriched carbohydrate and chitin metabolism pathways, indicating disrupted cytoskeletal dynamics and extracellular matrix integrity. Through this study, we elucidate the crucial roles of LvAQP11 in osmoregulation, molting, and muscle integrity in L. vannamei, providing novel insights into the multifunctional nature of superaquaporins beyond water transport. Full article
(This article belongs to the Special Issue Advances in Shrimp Physiology and Genomics)
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