Precision Fermentation: Applications in the Food and Beverage Industry, 2nd Edition

A special issue of Fermentation (ISSN 2311-5637). This special issue belongs to the section "Fermentation for Food and Beverages".

Deadline for manuscript submissions: 20 May 2026 | Viewed by 1260

Special Issue Editor


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Guest Editor
Department of Food Engineering, Center for Agricultural Sciences, Federal University of Ceará, Fortaleza 60020-18, CE, Brazil
Interests: food engineering; bioprocesses; waste valorization; agro-industrial residues; enzyme immobilization
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Special Issue Information

Dear Colleagues,

We are pleased to announce a Special Issue titled "Precision Fermentation: Applications in the Food and Beverage Industry, 2nd Edition", which will explore the latest advancements in this cutting-edge field. Precision fermentation is transforming the food and beverage sector by offering unprecedented control over product characteristics such as flavor, texture, and nutritional profiles. This technology enables the development of sustainable, high-quality products that meet the growing consumer demand for healthier and more environmentally friendly options.

We invite researchers, academics, and industry professionals to submit their original research, reviews, and case studies on innovative applications of precision fermentation. Contributions should explore new methods, technological advancements, and industrial-scale applications that push the boundaries of food and beverage production.

Topics of interest include, but are not limited to, the following:

  • Development of novel food ingredients through precision fermentation (proteins, bioactive peptides, postbiotics, flavors, and colors);
  • Precision fermentation for animal-free dairy proteins, plant-based protein enhancement, and alternative nutritional sources;
  • Production of prebiotics, probiotics, and postbiotics with applications in gut health and personalized nutrition;
  • Sustainable processes using alternative substrates (e.g., agro-industrial residues, CO₂, and gas fermentation);
  • Life cycle assessment (LCA) and environmental impact of precision fermentation compared to traditional methods;
  • Role of microbial engineering, synthetic biology, and biofoundries in strain development and process optimization;
  • Integration of artificial intelligence, machine learning, and automation in precision fermentation design and scale-up;
  • Emerging applications such as functional beverages, fermented plant-based products, and 3D food printing;
  • Industrial case studies on scaling up precision fermentation technologies and business models for commercialization;
  • Consumer acceptance, labeling, and regulatory challenges of precision-fermented food and beverage products.

We look forward to your contributions that will advance this exciting area of research.

Prof. Dr. Tiago Lima de Albuquerque
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • precision fermentation
  • synthetic biology
  • novel food ingredients
  • protein alternatives
  • animal-free dairy proteins
  • prebiotics and postbiotics
  • functional beverages
  • sustainable food production
  • industrial scale-up
  • consumer acceptance and regulation

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Published Papers (1 paper)

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Research

17 pages, 737 KB  
Article
Development of High Palmitoleic (16:1 n-7) Acid Oil by Fermentation of Microalgae
by Xiaoying Zhou, Mona Correa, Dino Athanasiadis, Veronica Benites, Bryce Doherty, Lucy Edy, Christy Piamonte, Gener Eliares, Marvin Cornejo, Ting Gong, Leon Parker, Manuel Oliveira, Walter Rakitsky, James Casey Lippmeier, Jessica M. Walter and Frédéric Destaillats
Fermentation 2026, 12(3), 160; https://doi.org/10.3390/fermentation12030160 - 18 Mar 2026
Cited by 1 | Viewed by 966
Abstract
Palmitoleic acid (POA; 16:1 n-7 or cis-9 16:1) is a bioactive monounsaturated fatty acid (FA) with emerging metabolic and skin-health relevance, yet conventional botanical and animal sources provide limited and variable levels. Here we report on the development of a high-yield POA [...] Read more.
Palmitoleic acid (POA; 16:1 n-7 or cis-9 16:1) is a bioactive monounsaturated fatty acid (FA) with emerging metabolic and skin-health relevance, yet conventional botanical and animal sources provide limited and variable levels. Here we report on the development of a high-yield POA product platform in the heterotrophic microalga Prototheca moriformis through targeted genetic engineering. A Δ9-fatty acid desaturase from Macadamia integrifolia (MiSAD1618) was integrated using a phosphite-based selection system. Primary screening identified stable transformants producing up to 54% POA of total fatty acids, compared to 0.8% in the parental strain. In 1 L shake-flask cultivation, POA reached up to 58.2% of total fatty acids. In a 1 L fed-batch fermentation, the engineered strain accumulated 47.8 g/L of lipids with 43.5% POA after 96 h of fermentation, corresponding to 20.8 g/L of POA. GC–MS analysis of 4,4-dimethyloxazoline (DMOX) derivatives confirmed that the major 16:1 isomer was 16:1 n-7 (Δ9). Together, these results establish P. moriformis as a scalable fermentation platform for producing POA-rich oil and highlight its potential as an efficient alternative source of POA, providing a foundation for further strain and process optimization toward commercial production. Full article
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