Special Issue "Application of Information Theory and Entropy in Cardiology"
Deadline for manuscript submissions: 30 September 2019
The human heart is a complex system composed of 5 billion autonomous cardiomyocytes that interact with each other with simple rules of operation and minimal central control. This interaction, through a reaction–diffusion process, leads to system behaviors at multiple scales. At the microscopic scale, the system behavior is characterized by transitions of cardiomyocyte states between excitation and relaxation. This relatively simple micro-scale behavior, by creating a series of traveling waves, can generate a multitude of arrhythmia at the macroscopic scale that controls the life and death of millions of human beings worldwide.
Like any other complex system, the heart is non-Markovian and non-ergodic, because it is out-of-equilibrium, path- and history-dependent, has a long memory, and has long-range interactions. As such, the heart violates Shannon–Khinchin’s composition axiom, a requirement for an entropy to be a measure for uncertainty. Nevertheless, information theory continues to be an important and useful tool to improve the understanding of heart disease and complex systems in general.
This Special Issue will focus on the application of information theory in Cardiology to understand 1) the relationship between micro- and macro-scale behaviors of the heart, 2) phase transitions in the cardiac system, and 3) the mechanism of heart disease.
Papers exploring topics from molecular to population scales will be considered. Papers describing information-theoretic approaches and findings that are applicable to other complex systems are particularly preferred. Theoretical and numerical investigations are also welcome.
Prof. Hiroshi Ashikaga
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Entropy is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.